5481 publication(s) trouvée(s)
Article scientifique
Influenza-associated pneumonia hospitalizations in Uganda, 2013-2016
BACKGROUND: Influenza is an important contributor to acute respiratory illness, including pneumonia, and results in substantial morbidity and mortality globally. …
Article scientifique
Meeting the demand of women affected by ongoing crisis: Increasing contraceptive prevalence in North and South Kivu, Democratic Republic of the Congo
CONTEXT: Over 20 years of conflict in the DRC, North and South Kivu have experienced cycles of stability and conflict, …
Article scientifique
Design of bile-based vesicles (BBVs) for hepatocytes specific delivery of Daclatasvir: Comparison of ex-vivo transenterocytic transport, in-vitro protein adsorption resistance and HepG2 cellular uptake of charged and β-sitosterol decorated vesicles
Daclatasvir is a new direct acting antiviral used in treatment of Hepatitis C virus, in an attempt to increase its …
Article scientifique
Reverse transcription recombinase polymerase amplification assay for rapid detection of canine associated rabies virus in Africa
Rabies is a neglected disease mostly affecting the developing world. Accurate and reliable diagnostic and surveillance data forms the foundation …
Article scientifique
Reliability of plasma HIV viral load testing beyond 24 hours: Insights gained from a study in a routine diagnostic laboratory
BACKGROUND: Viral load testing is key to monitoring response to anti-retroviral therapy (ART). However, in lower and middle income countries …
Article scientifique
Epidemiology and disease burden of tuberculosis in south of Tunisia over a 22-year period: Current trends and future projections
BACKGROUND: Tuberculosis (TB) is a public health problem worldwide. Characterizing its trends over time is a useful tool for decision-makers …
Article scientifique
Differential patterns of disease and injury in Mozambique: New perspectives from a pragmatic, multicenter, surveillance study of 7809 emergency presentations
BACKGROUND: There is a paucity of primary data to understand the overall pattern of disease and injuries as well as …
Article scientifique
Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with βS haplotype and α-thalassemia
This study investigated the effects of hydroxyurea (HU) on hematological, biochemical and inflammatory parameters in children with sickle cell anemia …
Article scientifique
A prospective study of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected children from high prevalence countries
BACKGROUND: The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected infants and young children is relatively understudied in regions endemic for …
Article scientifique
The magnitude and factors associated with work-related back and lower extremity musculoskeletal disorders among barbers in Gondar town, northwest Ethiopia, 2017: A cross-sectional study
BACKGROUND: Work-related back and lower extremity disorders often present remarkable health and economic burdens on societies. Occupational barbers are usually …
Article scientifique
Prehospital providers’ perspectives for clinical practice guideline implementation and dissemination: Strengthening guideline uptake in South Africa
BACKGROUND: In 2016 the first African emergency care clinical practice guideline (CPG) was developed for national uptake in the prehospital …
Article scientifique
A multilevel analysis of the determinants of missed opportunities for vaccination among children attending primary healthcare facilities in Kano, Nigeria: Findings from the pre-implementation phase of a collaborative quality improvement programme
BACKGROUND: We aimed to determine the factors that are responsible for missed opportunities for vaccination (MOV) among children aged 0-23 …
Article scientifique
Imbalance of antioxidant enzymes activities and trace elements levels in Ghanaian HIV-infected patients
Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) have been associated with high oxidative stress in HIV patients. The …
Article scientifique
The impact of the single exit price policy on a basket of generic medicines in South Africa, using a time series analysis from 1999 to 2014
BACKGROUND: Regulating pharmaceutical markets have become a key strategy by most governments in ensuring the availability and accessibility of quality …
Article scientifique
Status of HIV-infected patients classified as lost to follow up from a large antiretroviral program in southwest Nigeria
BACKGROUND: Loss to follow-up (LTFU) is a term used to classify patients no longer being seen in a clinical care …
Article scientifique
Sequencing and analysis of globally obtained human parainfluenza viruses 1 and 3 genomes
Human Parainfluenza viruses (HPIV) type 1 and 3 are important causes of respiratory tract infections in young children globally. HPIV …
Article scientifique
Multinomial modelling of TB/HIV co-infection yields a robust predictive signature and generates hypotheses about the HIV+TB+ disease state
BACKGROUND: Current diagnostics are inadequate to meet the challenges presented by co-infection with Mycobacterium tuberculosis (Mtb) and HIV, the leading …
Article scientifique
Readmission and death following hospitalization among people with HIV in South Africa
BACKGROUND: Additional approaches are needed to identify and provide targeted interventions to populations at continued risk for HIV-associated mortality. We …
Article scientifique
Missed opportunities for early infant diagnosis of HIV in rural North-Central Nigeria: A cascade analysis from the INSPIRE MoMent study
BACKGROUND: Early identification of HIV-infected infants for treatment is critical for survival. Efficient uptake of early infant diagnosis (EID) requires …
Article scientifique
The impact of interventions for the primary prevention of hypertension in Sub-Saharan Africa: A systematic review and meta-analysis
BACKGROUND: The prevalence of hypertension is highest in the African Region with 46% of adults aged 25 and above diagnosed …