92 publication(s) trouvée(s)
Article scientifique
Integrating HIV and hypertension management in low-resource settings: Lessons from Malawi
Pragna Patel and colleagues describe the implementation of a hypertension management model for HIV-infected people in Malawi.
Article scientifique
Global child and adolescent mental health: The orphan of development assistance for health
points• One-quarter of disability-adjusted life years (DALYs) for mental disorders and substance abuse is borne by those 24 years old …
Article scientifique
What’s coming for health science and policy in 2018? Global experts look ahead in their field
PLOS Medicine's commitment to bringing research and commentary on urgent, grievous, and underaddressed health needs to an open-access platform has …
Article scientifique
Estimated mortality on HIV treatment among active patients and patients lost to follow-up in 4 provinces of Zambia: Findings from a multistage sampling-based survey
BACKGROUND: Survival represents the single most important indicator of successful HIV treatment. Routine monitoring fails to capture most deaths. As …
Article scientifique
The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0
BACKGROUND: Verbal autopsy (VA) is a practical method for determining probable causes of death at the population level in places …
Article scientifique
Antiretroviral therapy and population mortality: Leveraging routine national data to advance policy
Reducing mortality from HIV, tuberculosis, and malaria with effective medicines, preventing diseases with immunisations, and improving access to safe water …
Article scientifique
Estimating the impact of antiretroviral treatment on adult mortality trends in South Africa: A mathematical modelling study
BACKGROUND: Substantial reductions in adult mortality have been observed in South Africa since the mid-2000s, but there has been no …
Article scientifique
Shortages of benzathine penicillin for prevention of mother-to-child transmission of syphilis: An evaluation from multi-country surveys and stakeholder interviews
BACKGROUND: Benzathine penicillin G (BPG) is the only recommended treatment to prevent mother-to-child transmission of syphilis. Due to recent reports …
Article scientifique
Treatment guidelines and early loss from care for people living with HIV in Cape Town, South Africa: A retrospective cohort study
BACKGROUND: South Africa has undergone multiple expansions in antiretroviral therapy (ART) eligibility from an initial CD4+ threshold of ≤200 cells/μl …
Article scientifique
The end of HIV: Still a very long way to go, but progress continues
In an Editorial accompanying PLOS Medicine's Special Issue on Advances in Prevention, Treatment and Cure of HIV/AIDS, Guest Editors Steven …
Article scientifique
Virological response and resistance among HIV-infected children receiving long-term antiretroviral therapy without virological monitoring in Uganda and Zimbabwe: Observational analyses within the randomised ARROW trial
BACKGROUND: Although WHO recommends viral load (VL) monitoring for those on antiretroviral therapy (ART), availability in low-income countries remains limited. …
Article scientifique
Prospects for passive immunity to prevent HIV infection
The need for better HIV prevention toolsDespite the widespread global rollout of antiretroviral therapy and its ability to reduce onward …
Article scientifique
Validity of a minimally invasive autopsy for cause of death determination in maternal deaths in Mozambique: An observational study
Despite global health efforts to reduce maternal mortality, rates continue to be unacceptably high in large parts of the world. …
Article scientifique
HIV self-testing among female sex workers in Zambia: A cluster randomized controlled trial
BACKGROUND: HIV self-testing (HIVST) may play a role in addressing gaps in HIV testing coverage and as an entry point …
Article scientifique
HIV pre-exposure prophylaxis and early antiretroviral treatment among female sex workers in South Africa: Results from a prospective observational demonstration project
BACKGROUND: Operational research is required to design delivery of pre-exposure prophylaxis (PrEP) and early antiretroviral treatment (ART). This paper presents …
Article scientifique
HIV prevalence and behavioral and psychosocial factors among transgender women and cisgender men who have sex with men in 8 African countries: A cross-sectional analysis
INTRODUCTION: Sub-Saharan Africa bears more than two-thirds of the worldwide burden of HIV; however, data among transgender women from the …
Article scientifique
malERA: An updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as overwhelming health, equity, and economic benefits.WHO and countries are …
Article scientifique
Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin
BACKGROUND: Transplacental transfer of maternal immunoglobulin G (IgG) to the fetus helps to protect against malaria and other infections in …
Article scientifique
Effectiveness of food supplements in increasing fat-free tissue accretion in children with moderate acute malnutrition: A randomised 2 × 2 × 3 factorial trial in Burkina Faso
BACKGROUND: Children with moderate acute malnutrition (MAM) are treated with lipid-based nutrient supplement (LNS) or corn-soy blend (CSB). We assessed …
Article scientifique
Lay worker-administered behavioral treatments for psychological distress in resource-limited settings: Time to move from evidence to practice?
Exposure to nonlethal violence is, apart from its resulting physical injury or other adverse health sequelae, one of the most …