381 publication(s) trouvée(s)
Article scientifique
Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates
Plasmodium falciparum delayed clearance with the use of artemisinin-based combination therapy (ACTs) has been reported in some African countries. Single …
Article scientifique
Molecular evidence for the transovarial passage of Babesia gibsoni in Haemaphysalis hystricis (Acari: Ixodidae) ticks from Taiwan: a novel vector for canine babesiosis
BACKGROUND: Babesia gibsoni is the predominant tick-borne protozoan blood parasite affecting dogs throughout the Oriental region. Babesia gibsoni is transmitted …
Article scientifique
Fine-scale spatial and temporal variation of clinical malaria incidence and associated factors in children in rural Malawi: a longitudinal study
BACKGROUND: Spatio-temporal variations in malaria burden are currently complex and costly to measure, but are important for decision-making. We measured …
Article scientifique
Elevated Plasmodium infection rates and high pyrethroid resistance in major malaria vectors in a forested area of Cameroon highlight challenges of malaria control
BACKGROUND: High coverage of long-lasting insecticidal nets (LLINs) is the cornerstone of the malaria control strategy of the national malaria …
Article scientifique
Native entomopathogenic Metarhizium spp. from Burkina Faso and their virulence against the malaria vector Anopheles coluzzii and non-target insects
Genetically enhanced Metarhizium pingshaense are being developed for malaria vector control in Burkina Faso. However, not much is known about …
Article scientifique
Occurrence and distribution of Giardia species in wild rodents in Germany
BACKGROUND: Giardiasis is an important gastrointestinal parasitic disease in humans and other mammals caused by the protozoan Giardia duodenalis. This …
Article scientifique
The current insecticide resistance status of Anopheles gambiae (s.l.) (Culicidae) in rural and urban areas of Bouaké, Côte d’Ivoire
BACKGROUND: Several studies were carried out in experimental hut station in areas surrounding the city of Bouaké, after the crisis …
Article scientifique
Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome
BACKGROUND: Schistosomiasis is a neglected tropical disease burdening millions of people. One drug, praziquantel, is currently used for treatment and …
Article scientifique
High proportions of asymptomatic and submicroscopic Plasmodium vivax infections in a peri-urban area of low transmission in the Brazilian Amazon
BACKGROUND: Population-based studies conducted in Latin America have shown a high proportion of asymptomatic and submicroscopic malarial infections. Considering efforts …
Article scientifique
Diverse laboratory colonies of Aedes aegypti harbor the same adult midgut bacterial microbiome
BACKGROUND: Host-associated microbes, collectively known as the microbiota, play an important role in the biology of multicellular organisms. In mosquito …
Article scientifique
Arenavirus infection correlates with lower survival of its natural rodent host in a long-term capture-mark-recapture study
BACKGROUND: Parasite evolution is hypothesized to select for levels of parasite virulence that maximise transmission success. When host population densities …
Article scientifique
Epidemiology of canine gastrointestinal helminths in sub-Saharan Africa
Dogs have a close association with humans providing companionship, security and a source of dietary protein. However, dogs are also …
Article scientifique
A multicentre, randomised, non-inferiority clinical trial comparing a nifurtimox-eflornithine combination to standard eflornithine monotherapy for late stage Trypanosoma brucei gambiense human African trypanosomiasis in Uganda
BACKGROUND: While the combination of nifurtimox and eflornithine (NECT) is currently recommended for the treatment of the late stage human …
Article scientifique
Latent class analysis to evaluate performance of point-of-care CCA for low-intensity Schistosoma mansoni infections in Burundi
BACKGROUND: Kato-Katz examination of stool smears is the field-standard method for detecting Schistosoma mansoni infection. However, Kato-Katz misses many active …
Article scientifique
Inclusion of edaphic predictors for enhancement of models to determine distribution of soil-transmitted helminths: the case of Zimbabwe
BACKGROUND: Reliable mapping of soil-transmitted helminth (STH) parasites requires rigorous statistical and machine learning algorithms capable of integrating the combined …
Article scientifique
Performance evaluation of existing immunoassays for Clonorchis sinensis infection in China
BACKGROUND: Clonorchiasis ranks among the most important food-borne parasitic diseases in China. However, due to low compliance to traditional fecal …
Article scientifique
Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model
BACKGROUND: Cystic echinococcosis is a global public health problem; however, the drugs (albendazole and mebendazole) currently recommended by WHO for …
Article scientifique
Urogenital schistosomiasis in Cabo Delgado, northern Mozambique: baseline findings from the SCORE study
BACKGROUND: The results presented here are part of a five-year cluster-randomised intervention trial that was implemented to understand how best …
Article scientifique
A cross-sectional study of the filarial and Leishmania co-endemicity in two ecologically distinct settings in Mali
Filariasis and leishmaniasis are two neglected tropical diseases in Mali. Due to distribution and associated clinical features, both diseases are …
Article scientifique
Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana
BACKGROUND: During a Plasmodium infection, exposure of human host immune cells to both the asexual and the sexual stages of …