133 publication(s) trouvée(s)
Article scientifique
Publisher Correction: Shared heritability and functional enrichment across six solid cancers
An amendment to this paper has been published and can be accessed via a link at the top of the …
Article scientifique
Pareto rules for malaria super-spreaders and super-spreading
Heterogeneity in transmission is a challenge for infectious disease dynamics and control. An 80-20 "Pareto" rule has been proposed to …
Article scientifique
A chemo-enzymatic oxidation cascade to activate C–H bonds with in situ generated H2O2
Abstract Continuous low-level supply or in situ generation of hydrogen peroxide (H2O2) is essential for the stability of unspecific peroxygenases, …
Article scientifique
Surface-kinetics mediated mesoporous multipods for enhanced bacterial adhesion and inhibition
Abstract Despite the importance of nanoparticle’s multipods topology in multivalent-interactions enhanced nano-bio interactions, the precise manipulation of multipods surface topological …
Article scientifique
The transferability of lipid loci across African, Asian and European cohorts
Abstract Most genome-wide association studies are based on samples of European descent. We assess whether the genetic determinants of blood …
Article scientifique
Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Tuberculous meningitis (TBM) is the most severe form of TB with high rates of mortality and morbidity. Here we conduct …
Article scientifique
Author Correction: Airway response to respiratory syncytial virus has incidental antibacterial effects
An amendment to this paper has been published and can be accessed via a link at the top of the …
Article scientifique
HIV-1 DNA sequence diversity and evolution during acute subtype C infection
Little is known about the genotypic make-up of HIV-1 DNA genomes during the earliest stages of HIV-1 infection. Here, we …
Article scientifique
Absorbable hemostatic hydrogels comprising composites of sacrificial templates and honeycomb-like nanofibrous mats of chitosan
The development of hemostatic technologies that suit a diverse range of emergency scenarios is a critical initiative, and there is …
Article scientifique
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly
A failure in optic fissure fusion during development can lead to blinding malformations of the eye. Here, we report a …
Article scientifique
Patterns of satellite tagged hen harrier disappearances suggest widespread illegal killing on British grouse moors
Identifying patterns of wildlife crime is a major conservation challenge. Here, we test whether deaths or disappearances of a protected …
Article scientifique
Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements
Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide …
Article scientifique
Aborted propagation of the Ethiopian rift caused by linkage with the Kenyan rift
Continental rift systems form by propagation of isolated rift segments that interact, and eventually evolve into continuous zones of deformation. …
Article scientifique
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02
Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite …
Article scientifique
Polymer gels with tunable ionic Seebeck coefficient for ultra-sensitive printed thermopiles
Measuring temperature and heat flux is important for regulating any physical, chemical, and biological processes. Traditional thermopiles can provide accurate …
Article scientifique
The indirect health effects of malaria estimated from health advantages of the sickle cell trait
Most estimates of the burden of malaria are based on its direct impacts; however, its true burden is likely to …
Article scientifique
Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy
Aminoacyl-tRNA synthetases (ARSs) function to transfer amino acids to cognate tRNA molecules, which are required for protein translation. To date, …
Article scientifique
Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features
The original version of this Article contained an error in the author affiliations. The affiliation of Kevin P. White with …
Article scientifique
Neurodevelopmental milestones and associated behaviours are similar among healthy children across diverse geographical locations
It is unclear whether early child development is, like skeletal growth, similar across diverse regions with adequate health and nutrition. …
Article scientifique
Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease
Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health …