3 publication(s) trouvée(s)
Article scientifique
Enhancement of dendritic persistent Na+ currents by mGluR5 leads to an advancement of spike timing with an increase in temporal precision
Timing and temporal precision of action potential generation are thought to be important for encoding of information in the brain. …
Article scientifique
Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer’s disease mouse models
Alzheimer's disease (AD) is characterized by neurotoxicity mediated by the accumulation of beta amyloid (Aβ) oligomers, causing neuronal loss and …
Article scientifique
Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition
Alzheimer’s disease (AD) is a neurodegenerative disorder associated with deficits in cognition and synaptic plasticity. While accumulation of amyloid β …