1031 publication(s) trouvée(s)
Article scientifique
Understanding human genetic factors influencing primaquine safety and efficacy to guide primaquine roll-out in a pre-elimination setting in southern Africa
BACKGROUND: Primaquine (PQ) is recommended as an addition to standard malaria treatments in pre-elimination settings due to its pronounced activity …
Article scientifique
Access and adequate utilization of malaria control interventions in rural Malawi: a descriptive quantitative study
BACKGROUND: Despite the availability of cost effective malaria control interventions, such as insecticide-treated bed nets (ITN), diagnosis and effective treatment …
Article scientifique
Cerebrospinal fluid Plasmodium falciparum histidine-rich protein-2 in pediatric cerebral malaria
BACKGROUND: Cerebral malaria (CM) causes a rapidly developing coma, and remains a major contributor to morbidity and mortality in malaria-endemic …
Article scientifique
Low risk of recurrence following artesunate–Sulphadoxine–pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan
Abstract Background First-line schizontocidal treatment for uncomplicated malaria in the Republic of the Sudan is artesunate (total dose 12 mg/kg) …
Article scientifique
Micro-epidemiology of malaria in an elimination setting in Central Vietnam
BACKGROUND: In Vietnam, malaria persists in remote forested regions where infections are spatially heterogeneous, mostly asymptomatic and with low parasite …
Article scientifique
Reactive case detection of Plasmodium falciparum in western Kenya highlands: effective in identifying additional cases, yet limited effect on transmission
BACKGROUND: Identifying asymptomatic reservoirs of malaria parasites using index cases as entry points into the community is potentially a cost-effective …
Article scientifique
Efficacy and safety of artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Sudan: a systematic review and meta-analysis
Malaria is a major public health problem in endemic countries including Sudan, where about 75% of populations are at risk. …
Article scientifique
Insecticide resistance in Anopheles arabiensis populations from Dakar and its suburbs: role of target site and metabolic resistance mechanisms
BACKGROUND: Urban malaria is an increasing concern in most of the sub-Saharan Africa countries. In Dakar, the capital city of …
Article scientifique
Uptake of intermittent preventive treatment and pregnancy outcomes: health facilities and community surveys in Chókwè district, southern Mozambique
BACKGROUND: Malaria in pregnancy leads to serious adverse effects on the mother and the child and accounts for 75,000-200,000 infant …
Article scientifique
Investigating insecticide resistance and knock-down resistance (kdr) mutation in Dielmo, Senegal, an area under long lasting insecticidal-treated nets universal coverage for 10 years
BACKGROUND: The use of insecticides, through indoor residual spraying and long-lasting insecticide-treated nets (LLINs), is essential to control malaria vectors. …
Article scientifique
Nationwide insecticide resistance status and biting behaviour of malaria vector species in the Democratic Republic of Congo
BACKGROUND: Globally, the Democratic Republic of Congo (DRC) accounted for 9% of malaria cases and 10% of malaria deaths in …
Article scientifique
Pattern of all-causes and cause-specific mortality in an area with progressively declining malaria burden in Korogwe district, north-eastern Tanzania
BACKGROUND: Although death records are useful for planning and monitoring health interventions, such information is limited in most developing countries. …
Article scientifique
Private sector malaria RDT initiative in Nigeria: lessons from an end-of-project stakeholder engagement meeting
The malaria rapid diagnosis testing (RDT) landscape is rapidly evolving in health care delivery in Nigeria with many stakeholders playing …
Article scientifique
Effect of nutrient supplementation on the acquisition of humoral immunity to Plasmodium falciparum in young Malawian children
BACKGROUND: There is evidence that suggests that undernutrition has a detrimental effect on malarial immunity in children. The aim of …
Article scientifique
Improvement of malaria diagnostic system based on acridine orange staining
BACKGROUND: Rapid diagnosis of malaria using acridine orange (AO) staining and a light microscope with a halogen lamp and interference …
Article scientifique
Accuracy and impact of spatial aids based upon satellite enumeration to improve indoor residual spraying spatial coverage
BACKGROUND: Indoor residual spraying (IRS) is a key tool in the fight to control, eliminate and ultimately eradicate malaria. IRS …
Article scientifique
Direct whole-genome sequencing of Plasmodium falciparum specimens from dried erythrocyte spots
BACKGROUND: Plasmodium falciparum malaria remains a major health burden and genomic research represents one of the necessary approaches for continued …
Article scientifique
Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population
BACKGROUND: Severe forms of malaria (SM) are an outcome of Plasmodium falciparum infection and can cause death especially in children …
Article scientifique
Plasmodium falciparum diagnostic tools in HIV-positive under-5-year-olds in two ART clinics in Ghana: are there missed infections?
BACKGROUND: Plasmodium falciparum, the most dominant species in sub-Saharan Africa, causes the most severe clinical malaria manifestations. In resource-limited Ghana, …
Article scientifique
True malaria prevalence in children under five: Bayesian estimation using data of malaria household surveys from three sub-Saharan countries
BACKGROUND: Malaria is one of the major causes of childhood death in sub-Saharan countries. A reliable estimation of malaria prevalence …