1006 publication(s) trouvée(s)
Article scientifique
Monitoring health systems readiness and inpatient malaria case-management at Kenyan county hospitals
BACKGROUND: Change of severe malaria treatment policy from quinine to artesunate, a major malaria control advance in Africa, is compromised …
Article scientifique
Malaria determining risk factors at the household level in two rural villages of mainland Equatorial Guinea
BACKGROUND: After the introduction of an artemisinin-based combination therapy, the reduction of prevalence of malaria infections has shown a remarkable …
Article scientifique
Evaluation of malaria rapid diagnostic test (RDT) use by community health workers: a longitudinal study in western Kenya
BACKGROUND: Malaria rapid diagnostic tests (RDTs) are a simple, point-of-care technology that can improve the diagnosis and subsequent treatment of …
Article scientifique
Awareness, perceptions and intent to comply with the prospective malaria vaccine in parts of South Eastern Nigeria
There are potentials of a malaria vaccine being developed sooner than expected. While focus is more on the development of …
Article scientifique
Pyronaridine–artesunate and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial
BACKGROUND: Pyronaridine-artesunate is a novel artemisinin-based combination therapy. The efficacy and safety of pyronaridine-artesunate were compared with artemether-lumefantrine for the …
Article scientifique
Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa
BACKGROUND: Parasite genetic diversity and multiplicity of infection (MOI) affect clinical outcomes, response to drug treatment and naturally-acquired or vaccine-induced …
Article scientifique
Anopheles arabiensis in Sudan: a noticeable tolerance to urban polluted larval habitats associated with resistance to Temephos
It has been documented that unplanned urbanization leads to the exposure of members of the Anopheles vectors to a range …
Article scientifique
A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants
BACKGROUND: Given the risk of artemisinin resistance spreading from the Greater Mekong sub-region, prospective monitoring in sub-Saharan Africa should be …
Article scientifique
Quantifying malaria endemicity in Ethiopia through combined application of classical methods and enzyme-linked immunosorbent assay: an initial step for countries with low transmission initiating elimination programme
BACKGROUND: In the context of reduced transmission of malaria, it is essential to re-evaluate and determine the level of transmission …
Article scientifique
Wash-resistance of pirimiphos-methyl insecticide treatments of window screens and eave baffles for killing indoor-feeding malaria vector mosquitoes: an experimental hut trial, South East of Zambia
BACKGROUND: The effectiveness of long-lasting insecticidal-treated nets (LLINs) and indoor residual spraying (IRS) for malaria control is threatened by resistance …
Article scientifique
Targeted application of an organophosphate-based paint applied on windows and doors against Anopheles coluzzii resistant to pyrethroids under real life conditions in Vallée du Kou, Burkina Faso (West Africa)
A novel strategy applying an organophosphate-based insecticide paint on doors and windows in combination with long-lasting insecticide-treated nets (LLINs) was …
Article scientifique
Elevated IL-17 levels in semi-immune anaemic mice infected with Plasmodium berghei ANKA
Alterations in inflammatory cytokines and genetic background of the host contribute to the outcome of malaria infection. Despite the promising …
Article scientifique
Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei
Increasing resistance to current anti-malarial therapies requires a renewed effort in searching for alternative therapies to combat this challenge, and …
Article scientifique
Using participatory risk analysis to develop a song about malaria for young children in Limpopo Province, South Africa
BACKGROUND: In 2015, malaria infected over 212 million people and killed over 429,000 individuals, mostly children under 5 years of …
Article scientifique
High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection
BACKGROUND: Increased susceptibility to malaria during pregnancy is not completely understood. Cellular immune responses mediate both pathology and immunity but …
Article scientifique
Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium
BACKGROUND: In the context of malaria elimination/eradication, drugs that are effective against the different developmental stages of the parasite are …
Article scientifique
Scaling up malaria intervention “packages” in Senegal: using cost effectiveness data for improving allocative efficiency and programmatic decision-making
BACKGROUND: Senegal's National Malaria Control Programme (NMCP) implements control interventions in the form of targeted packages: (1) scale-up for impact …
Article scientifique
Potent antiplasmodial extracts and fractions from Terminalia mantaly and Terminalia superba
The emergence and spread of malaria parasites resistant to artemisinin-based combination therapy stresses the need for novel drugs against malaria. …
Article scientifique
Local knowledge and practices towards malaria in an irrigated farming community in Ghana
BACKGROUND: Although malaria is endemic across Ghana, the risk is generally elevated for residents living in and around stagnant water …
Article scientifique
The effect of case management and vector-control interventions on space–time patterns of malaria incidence in Uganda
BACKGROUND: Electronic reporting of routine health facility data in Uganda began with the adoption of the District Health Information Software …