919 publication(s) trouvée(s)
Article scientifique
Evaluation of loop-mediated isothermal amplification as a surveillance tool for malaria in reactive case detection moving towards elimination
BACKGROUND: As malaria transmission decreases, the proportion of infections that are asymptomatic at any given time increases. This poses a …
Article scientifique
Intermittent screening and treatment with artemether–lumefantrine versus intermittent preventive treatment with sulfadoxine–pyrimethamine for malaria in pregnancy: a facility-based, open-label, non-inferiority trial in Nigeria
BACKGROUND: The spread of SP resistance may compromise the effectiveness of intermittent preventive treatment of malaria in pregnancy (MiP) with …
Article scientifique
Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children
BACKGROUND: The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem …
Article scientifique
Identifying risk factors for the development of sepsis during adult severe malaria
BACKGROUND: Severe falciparum malaria can be compounded by bacterial sepsis, necessitating antibiotics in addition to anti-malarial treatment. The objective of …
Article scientifique
Characterization of T cell activation and regulation in children with asymptomatic Plasmodium falciparum infection
BACKGROUND: Asymptomatic Plasmodium infections are characterized by the absence of clinical disease and the ability to restrict parasite replication. Increasing …
Article scientifique
Trends of Plasmodium falciparum prevalence in two communities of Muheza district North-eastern Tanzania: correlation between parasite prevalence, malaria interventions and rainfall in the context of re-emergence of malaria after two decades of progressively declining transmission
BACKGROUND: Although the recent decline of malaria burden in some African countries has been attributed to a scale-up of interventions, …
Article scientifique
Evidence for histidine-rich protein 2 immune complex formation in symptomatic patients in Southern Zambia
BACKGROUND: Rapid diagnostic tests based on histidine-rich protein 2 (HRP2) detection are the primary tools used to detect Plasmodium falciparum …
Article scientifique
Environmental health risks and benefits of the use of mosquito coils as malaria prevention and control strategy
BACKGROUND: Malaria is an infectious disease that causes many deaths in sub-Saharan Africa. In resource-poor malaria endemic communities, mosquito coils …
Article scientifique
High efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Muheza and Kigoma Districts, Tanzania
BACKGROUND: Artemether-lumefantrine (AL) is the recommended first-line artemisinin-based combination therapy (ACT) for the treatment of uncomplicated falciparum malaria in most …
Article scientifique
Community-based malaria control in southern Malawi: a description of experimental interventions of community workshops, house improvement and larval source management
BACKGROUND: Increased engagement of communities has been emphasized in global plans for malaria control and elimination. Three interventions to reinforce …
Article scientifique
The role of the Deki Reader™ in malaria diagnosis, treatment and reporting: findings from an Africare pilot project in Nigeria
BACKGROUND: The Deki Reader is a diagnostic device used with rapid diagnostic tests (RDTs) and linked to an online database …
Article scientifique
Caregivers’ knowledge and utilization of long-lasting insecticidal nets among under-five children in Osun State, Southwest, Nigeria
BACKGROUND: Utilization of long-lasting insecticidal nets (LLIN) has been associated with reduction of malaria incidence, especially among children. The 2013 …
Article scientifique
Reduction of malaria prevalence after introduction of artemisinin-combination-therapy in Mbeya Region, Tanzania: results from a cohort study with 6773 participants
BACKGROUND: A marked decline in malaria morbidity and mortality has been reported after the introduction of artemisinin-based combination therapy (ACT) …
Article scientifique
A cross-sectional study of asymptomatic Plasmodium falciparum infection burden and risk factors in general population children in 12 villages in northern Uganda
Plasmodium falciparum malaria is an important cause of morbidity in northern Uganda. This study was undertaken to assess village-, household-, …
Article scientifique
Effectiveness of pregnant women’s active participation in their antenatal care for the control of malaria and anaemia in pregnancy in Ghana: a cluster randomized controlled trial
BACKGROUND: The burden of malaria and anaemia in pregnancy remains high despite the availability of proven efficacious antenatal care interventions. …
Article scientifique
Household-level and surrounding peri-domestic environmental characteristics associated with malaria vectors Anopheles arabiensis and Anopheles funestus along an urban–rural continuum in Blantyre, Malawi
BACKGROUND: Malaria is increasing in some recently urbanized areas that historically were considered lower risk. Understanding what drives urban transmission …
Article scientifique
Prevalence and risk factors for asymptomatic malaria and genotyping of glucose 6-phosphate (G6PD) deficiencies in a vivax-predominant setting, Lao PDR: implications for sub-national elimination goals
BACKGROUND: Lao People Democratic Republic (PDR; Laos), a landlocked country in Southeast Asia, has made important progress in reducing malaria …
Article scientifique
Achievement of malaria pre-elimination in Cape Verde according to the data collected from 2010 to 2016
BACKGROUND: Malaria, despite being preventable and treatable, continues to be a major public health problem worldwide. The archipelago nation of …
Article scientifique
External quality assessment of malaria microscopy diagnosis in selected health facilities in Western Oromia, Ethiopia
BACKGROUND: Accurate early diagnosis and prompt treatment are one of the key strategies to control and prevent malaria disease. External …
Article scientifique
Bed nets used to protect against malaria do not last long in a semi-arid area of Ethiopia: a cohort study
Long-lasting insecticidal nets (LLINs) are a key tool for malaria prevention and control. Currently, the recommended serviceable life of an …