728 publication(s) trouvée(s)
Article scientifique
Molecular surveillance of the Pfmdr1 N86Y allele among Congolese pregnant women with asymptomatic malaria
BACKGROUND: Malaria in pregnancy is associated with considerable morbidity and mortality. Regular surveillance of artemisinin-based combination therapy tolerance, or molecular …
Article scientifique
Measuring antibody avidity to Plasmodium falciparum merozoite antigens using a multiplex immunoassay approach
Abstract Background Antibodies (Ab) play a significant role in immunity to Plasmodium falciparum malaria. Usually, following repeated exposure to pathogens, …
Article scientifique
Prevalence of pfdhfr and pfdhps mutations in Plasmodium falciparum associated with drug resistance among pregnant women receiving IPTp-SP at Msambweni County Referral Hospital, Kwale County, Kenya
BACKGROUND: Prevention and treatment of malaria during pregnancy is crucial in dealing with maternal mortality and adverse fetal outcomes. The …
Article scientifique
Scaling up malaria elimination management and leadership: a pilot in three provinces in Zimbabwe, 2016–2018
BACKGROUND: Focus for improved malaria programme performance is often placed on the technical challenges, while operational issues are neglected. Many …
Article scientifique
Molecular assessment of kelch13 non-synonymous mutations in Plasmodium falciparum isolates from Central African Republic (2017–2019)
BACKGROUND: Over the last decade, artemisinin-based combination therapy (ACT) has contributed substantially to the decrease in malaria-related morbidity and mortality. …
Article scientifique
Comparison of swarming, mating performance and longevity of males Anopheles coluzzii between individuals fed with different natural fruit juices in laboratory and semi-field conditions
BACKGROUND: It is assumed that malaria vectors feed on locally available nectar sources to obtain energy. Sugar feeding is energetically …
Article scientifique
Improving the efficiency of reactive case detection for malaria elimination in southern Zambia: a cross-sectional study
BACKGROUND: Reactive case detection (RCD) seeks to enhance malaria surveillance and control by identifying and treating parasitaemic individuals residing near …
Article scientifique
Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women
BACKGROUND: While sub-microscopic malarial infections are frequent and potentially deleterious during pregnancy, routine molecular detection is still not feasible. This …
Article scientifique
Comparing the durability of the long-lasting insecticidal nets DawaPlus® 2.0 and DuraNet© in northwest Democratic Republic of Congo
Abstract Background Anecdotal reports from DRC suggest that long-lasting insecticidal nets (LLIN) distributed through mass campaigns in DRC may not …
Article scientifique
Evaluation of human-baited double net trap and human-odour-baited CDC light trap for outdoor host-seeking malaria vector surveillance in Kenya and Ethiopia
BACKGROUND: Surveillance of outdoor host-seeking malaria vectors is crucial to monitor changes in vector biting behaviour and evaluate the impact …
Article scientifique
The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019
BACKGROUND: African Traditional Medicine (ATM) is used for the healthcare of about 80% of the rural populations of the continent …
Article scientifique
Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia
BACKGROUND: The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The …
Article scientifique
Sub-national stratification of malaria risk in mainland Tanzania: a simplified assembly of survey and routine data
Abstract Background Recent malaria control efforts in mainland Tanzania have led to progressive changes in the prevalence of malaria infection …
Article scientifique
The role of complement immune response on artemisinin-based combination therapy in a population from malaria endemic region of Western Kenya
BACKGROUND: Naturally acquired immunity (NAI), which is characterized by protection against overt clinical disease and high parasitaemia, is acquired with …
Article scientifique
Spatiotemporal analysis of insecticide-treated net use for children under 5 in relation to socioeconomic gradients in Central and East Africa
BACKGROUND: Insecticide-treated net (ITN) use is the core intervention among the strategies against malaria in sub-Saharan Africa (SSA) and the …
Article scientifique
Malaria knowledge and experiences with community health workers among recently pregnant women in Malawi
BACKGROUND: The World Health Organization recommends three or more doses of intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) to …
Article scientifique
Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets
Abstract Background Dissolution of artemether (ART) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets …
Article scientifique
A validation of the Malaria Atlas Project maps and development of a new map of malaria transmission in Sokoto, Nigeria: a cross-sectional study using geographic information systems
BACKGROUND: Malaria remains a major cause of morbidity and mortality among children in Africa. There is inadequate information regarding malaria …
Article scientifique
Assessment of platelet indices and platelet activation markers in children with Plasmodium falciparum malaria
BACKGROUND: Plasmodium falciparum malaria remains one of the world's major infectious diseases that cause most morbidity and mortality, particularly in …
Article scientifique
Trend of declining bed net utilization among pregnant women in Ethiopia: new data from the Arba Minch Health and Demographic Surveillance System, 2010–2016
BACKGROUND: Bed net utilization is one of the important methods of malaria prevention. Malaria during pregnancy is one of the …
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