17 publication(s) trouvée(s)
Article scientifique
The role of epigenetics in respiratory health in urban populations in low and middle-income countries
As urbanization increases in low- and middle-income countries (LMICs), urban populations will be increasingly exposed to a range of environmental …
Article scientifique
Non-alcoholic fatty liver disease in Africa: a hidden danger
There is a dearth of data on the burden and spectrum of non-alcoholic fatty liver disease (NAFLD) in African populations. …
Article scientifique
An upward trajectory of genomic publications from Africa: cautious optimism for a turning tide
Article scientifique
Strategies for screening cord blood for a public cord blood bank in high HIV prevalence regions
The probability of a Black African finding a matched unrelated donor for a hematopoietic stem cell transplant is minimal due …
Article scientifique
HIV treatment is associated with a twofold higher probability of raised triglycerides: pooled analyses in 21 023 individuals in sub-Saharan Africa
BACKGROUND: Anti-retroviral therapy (ART) regimes for HIV are associated with raised levels of circulating triglycerides (TG) in western populations. However, …
Article scientifique
Body mass index and wealth index: positively correlated indicators of health and wealth inequalities in Nairobi slums
INTRODUCTION: (SES). However, an in-depth investigation of the relationship between BMI and wealth index is lacking for urban slum settings. …
Article scientifique
Genomics research in Africa and its impact on global health: insights from African researchers
Africa may be heading for an era of genomics medicine. There are also expectations that genomics may play a role …
Article scientifique
Genetics of breast cancer in African populations: a literature review
Breast cancer (BC) is one of the most complex, diverse and leading cause of death in women worldwide. The present …
Article scientifique
Novel polymorphisms in TICAM2 and NOD1 associated with tuberculosis progression phenotypes in Ethiopian populations
Background Infection by Mycobacterium tuberculosis (Mtb) is a necessary but not sufficient cause for tuberculosis (TB). Although numerous studies suggest …
Article scientifique
Infectious disease research and the gender gap
Historically, women have been less likely to be supported through higher degree training programmes, and they continue to hold more …
Article scientifique
Strengthening human genetics research in Africa: report of the 9th meeting of the African Society of Human Genetics in Dakar in May 2016
The 9th meeting of the African Society of Human Genetics, in partnership with the Senegalese Cancer Research and Study Group …
Article scientifique
The long road to elimination: malaria mortality in a South African population cohort over 21 years
BACKGROUND: Malaria elimination is on global agendas following successful transmission reductions. Nevertheless moving from low to zero transmission is challenging. …
Article scientifique
Beta-globin gene haplotypes and selected Malaria-associated variants among black Southern African populations
Partial carrier-resistance toPlasmodium falciparummalaria conferred by the sickle cell (HbS) mutation has resulted in the local amplification and positive selection …
Article scientifique
Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot
Abstract Epstein Barr virus (EBV) infects 95% of the global population and is associated with up to 2% of cancers …
Article scientifique
Disease burden and the role of pharmacogenomics in African populations
BACKGROUND: The burden of communicable and non-communicable diseases in Sub-Saharan Africa poses a challenge in achieving quality healthcare. Although therapeutic …
Article scientifique
Developing the science and methods of community engagement for genomic research and biobanking in Africa
Historically, community engagement (CE) in research has been implemented in the fields of public health, education and agricultural development. In …
Article scientifique
The role of women's leadership and gender equity in leadership and health system strengthening
Gender equity is imperative to the attainment of healthy lives and wellbeing of all, and promoting gender equity in leadership …