8 publication(s) trouvée(s)
Article scientifique
Anoctamin 1/TMEM16A controls intestinal Cl− secretion induced by carbachol and cholera toxin
Calcium-activated chloride channels (CaCCs) mediate numerous physiological functions and are best known for the transport of electrolytes and water in …
Article scientifique
METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice
Physical activity has many beneficial effects on metabolic disorders, such as obesity, insulin resistance, and diabetes. Meteorin-like protein (METRNL), a …
Article scientifique
Assessment of genetic factor and depression interactions for asthma symptom severity in cohorts of childhood and elderly asthmatics
It is well known that depression is associated with asthma symptoms. We assessed the combined effects of genetic factors and …
Article scientifique
Enhancement of 5-HT2A receptor function and blockade of Kv1.5 by MK801 and ketamine: implications for PCP derivative-induced disease models
MK801 and ketamine, which are phencyclidine (PCP) derivative N-methyl-d-aspartate receptor (NMDAr) blockers, reportedly enhance the function of 5-hydroxytryptamine (HT)-2A receptors …
Article scientifique
Whither systems medicine?
New technologies to generate, store and retrieve medical and research data are inducing a rapid change in clinical and translational …
Article scientifique
Stimulation of osteoclast migration and bone resorption by C–C chemokine ligands 19 and 21
Osteoclasts are responsible for the bone erosion associated with rheumatoid arthritis (RA). The upregulation of the chemokines CCL19 and CCL21 …
Article scientifique
Effect of blood type on anti-α-Gal immunity and the incidence of infectious diseases
The identification of factors affecting the susceptibility to infectious diseases is essential toward reducing their burden on the human population. …
Article scientifique
Progress of antibody-based inhibitors of the HGF–cMET axis in cancer therapy
Dysregulated receptor tyrosine kinase signaling in human cancer cells leads to tumor progression, invasion and metastasis. The receptor tyrosine kinase …