13 publication(s) trouvée(s)
Article scientifique
Modulation of doxorubicin-induced expression of the multidrug resistance gene in breast cancer cells by diltiazem and protection against cardiotoxicity in experimental animals
BACKGROUND: Doxorubicin (DOX) is one of the most important anticancer agents used in treating breast cancer. However, chronic cardiotoxicity and …
Article scientifique
In silico analysis excavates potential biomarkers by constructing miRNA-mRNA networks between non-cirrhotic HCC and cirrhotic HCC
Mounting evidences have demonstrated that HCC patients with or without cirrhosis possess different clinical characteristics, tumor development and prognosis. However, …
Article scientifique
Effect of Gallic acid in potentiating chemotherapeutic effect of Paclitaxel in HeLa cervical cancer cells
BACKGROUND: Cervical cancer is the fourth most common cancer affecting women worldwide. Paclitaxel/Carboplatin is one of the most commonly prescribed …
Article scientifique
Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma
BACKGROUND: Oxaliplatin-based chemotherapy is widely used to treat hepatocellular carcinoma (HCC). Recent studies suggested that therapeutic resistance of tumors was …
Article scientifique
Correction to: Chemosensitizing and nephroprotective effect of resveratrol in cisplatin-treated animals
Following publication of the original article [1], the authors notified us of an error in the spelling of second author’s …
Article scientifique
Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization
BACKGROUND: The estrogen metabolite 2-methoxyestradiol (2ME2) and a number of synthesised derivatives have been shown to bind to microtubules thereby …
Article scientifique
A novel non-sulphamoylated 2-methoxyestradiol derivative causes detachment of breast cancer cells by rapid disassembly of focal adhesions
BACKGROUND: 2-Methoxyestradiol (2ME2) is an estradiol metabolite with well documented antiproliferative properties in many cancer cell lines. However, it is …
Article scientifique
Marsdenia tenacissima extract induces apoptosis and suppresses autophagy through ERK activation in lung cancer cells
BACKGROUND: extract (MTE) shows significant anti-proliferation activity against non-small cell lung cancer (NSCLC) cells, but the underlying mechanisms remain unclear. …
Article scientifique
An overview of the role of platelets in angiogenesis, apoptosis and autophagy in chronic myeloid leukaemia
Amongst males, leukaemia is the most common cause of cancer-related death in individuals younger than 40 years of age whereas …
Article scientifique
EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP
BACKGROUND: Rituximab combined with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) is used as standard frontline regimen for diffuse large B-cell …
Article scientifique
Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa
BACKGROUND: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as …
Article scientifique
HLBT-100: a highly potent anti-cancer flavanone from Tillandsia recurvata (L.) L.
The incidence and mortalities from cancers remain on the rise worldwide. Despite significant efforts to discover and develop novel anticancer …
Article scientifique
Biomechanical cell regulatory networks as complex adaptive systems in relation to cancer
Physiological structure and function of cells are maintained by ongoing complex dynamic adaptive processes in the intracellular molecular pathways controlling …