53 publication(s) trouvée(s)
Article scientifique
Gender differences in tuberculosis treatment outcomes: a post hoc analysis of the REMoxTB study
BACKGROUND: In the REMoxTB study of 4-month treatment-shortening regimens containing moxifloxacin compared to the standard 6-month regimen for tuberculosis, the …
Article scientifique
Complex interactions between malaria and malnutrition: a systematic literature review
BACKGROUND: Despite substantial improvement in the control of malaria and decreased prevalence of malnutrition over the past two decades, both …
Article scientifique
Global variation in bacterial strains that cause tuberculosis disease: a systematic review and meta-analysis
BACKGROUND: The host, microbial, and environmental factors that contribute to variation in tuberculosis (TB) disease are incompletely understood. Accumulating evidence …
Article scientifique
Pathways to ensure universal and affordable access to hepatitis C treatment
Direct-acting antivirals (DAAs) have dramatically changed the landscape of hepatitis C treatment and prevention. The World Health Organization has called …
Article scientifique
Inflammation and micronutrient biomarkers predict clinical HIV treatment failure and incident active TB in HIV-infected adults: a case-control study
BACKGROUND: Various individual biomarkers of inflammation and micronutrient status, often correlated with each other, are associated with adverse treatment outcomes …
Article scientifique
Healthcare service delivery to refugee children from the Democratic Republic of Congo living in Durban, South Africa: a caregivers’ perspective
Refugees are generally considered a vulnerable population, with refugee children (newborn and young children) being particularly so. Access to healthcare …
Article scientifique
Do hotspots fuel malaria transmission: a village-scale spatio-temporal analysis of a 2-year cohort study in The Gambia
BACKGROUND: Despite the biological plausibility of hotspots fueling malaria transmission, the evidence to support this concept has been mixed. If …
Article scientifique
The socioeconomic profile of alcohol-attributable mortality in South Africa: a modelling study
BACKGROUND: Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher …
Article scientifique
Cross-border movement, economic development and malaria elimination in the Kingdom of Saudi Arabia
Malaria at international borders presents particular challenges with regards to elimination. International borders share common malaria ecologies, yet neighboring countries …
Article scientifique
Recurrence quantification analysis of resting state EEG signals in autism spectrum disorder – a systematic methodological exploration of technical and demographic confounders in the search for biomarkers
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a worldwide prevalence of 1-2%. In low-resource environments, in particular, …
Article scientifique
Effective coverage of essential inpatient care for small and sick newborns in a high mortality urban setting: a cross-sectional study in Nairobi City County, Kenya
BACKGROUND: Effective coverage requires that those in need can access skilled care supported by adequate resources. There are, however, few …
Article scientifique
Efficacy and safety of ascending doses of praziquantel against Schistosoma haematobium infection in preschool-aged and school-aged children: a single-blind randomised controlled trial
BACKGROUND: Despite decades of experience with praziquantel treatment in school-aged children (SAC) and adults, we still face considerable knowledge gaps …
Article scientifique
Pretreatment chest x-ray severity and its relation to bacterial burden in smear positive pulmonary tuberculosis
Chest radiographs are used for diagnosis and severity assessment in tuberculosis (TB). The extent of disease as determined by smear …
Article scientifique
Prevalence, risk factors and behavioural and emotional comorbidity of acute seizures in young Kenyan children: a population-based study
BACKGROUND: Acute symptomatic seizures and febrile seizures are common in children admitted to hospitals in Africa and may be markers …
Article scientifique
Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa
BACKGROUND: Hyperlactataemia (HL) is a biomarker of disease severity that predicts mortality in patients with sepsis and malaria. Lactate clearance …
Article scientifique
Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study
BACKGROUND: Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial …
Article scientifique
Hospital Mortality – a neglected but rich source of information supporting the transition to higher quality health systems in low and middle income countries
BACKGROUND: There is increasing focus on the strength of primary health care systems in low and middle-income countries (LMIC). There …
Article scientifique
Syrian refugees in Greece: experience with violence, mental health status, and access to information during the journey and while in Greece
BACKGROUND: Since 2015, Europe has been facing an unprecedented arrival of refugees and migrants: more than one million people entered …
Article scientifique
Micronutrient powders to combat anaemia in young children: do they work?
In 2016, the World Health Organization (WHO) recommended point-of-use fortification of complementary foods with iron-containing micronutrient powders to improve iron …
Article scientifique
Correction to: An exploration of mortality risk factors in non-severe pneumonia in children using clinical data from Kenya
CORRECTION: The original article contains an omission in the Acknowledgements sub-section of the Declarations.