7 publication(s) trouvée(s)
Article scientifique
Potential risks and solutions for sharing genome summary data from African populations
Genome data from African population can substantially assist the global effort to identify aetiological genetic variants, but open access to …
Article scientifique
Gene expression profiling in blood from cerebral malaria patients and mild malaria patients living in Senegal
BACKGROUND: Plasmodium falciparum malaria remains a major health problem in Africa. The mechanisms of pathogenesis are not fully understood. Transcriptomic …
Article scientifique
FTO haplotyping underlines high obesity risk for European populations
BACKGROUND: Fat mass and obesity-associated (FTO) gene has been under close investigation since the discovery of its high impact on …
Article scientifique
Insights into the genetics of blood pressure in black South African individuals: the Birth to Twenty cohort
Cardiovascular diseases (CVDs) are the leading cause of non-communicable disease deaths globally, with hypertension being a major risk factor contributing …
Article scientifique
Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects
BACKGROUND: Ritodrine is a commonly used tocolytic to prevent preterm labour. However, it can cause unexpected serious adverse reactions, such …
Article scientifique
In silico identification of potential key regulatory factors in smoking-induced lung cancer
BACKGROUND: Lung cancer is a leading cause of cancer-related death worldwide and is the most commonly diagnosed cancer. Like other …
Article scientifique
Evolution of Translational Bioinformatics: lessons learned from TBC 2016
Translational bioinformatics (TBI) is a relatively young discipline that spans a wide spectrum from data to diagnostics and therapeutics. TBI …