734 publication(s) trouvée(s)
Article scientifique
Characteristics of human encounters and social mixing patterns relevant to infectious diseases spread by close contact: a survey in Southwest Uganda
BACKGROUND: Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet …
Article scientifique
Factors affecting adherence to antiretroviral therapy among pregnant women in the Eastern Cape, South Africa
BACKGROUND: Context-specific factors influence adherence to antiretroviral therapy (ART) among pregnant women living with HIV. Gaps exist in the understanding …
Article scientifique
Mycobacterium tuberculosis thymidylate kinase antigen assays for designating incipient, high-risk latent M.tb infection
BACKGROUND: Precise designation of high risk forms of latent Mycobacterium tuberculosis-M.tb infections (LTBI) is impossible. Delineation of high-risk LTBI can, …
Article scientifique
Household contact non-attendance of clinical evaluation for tuberculosis: a pilot study in a high burden district in South Africa
BACKGROUND: In 2012, the World Health Organization launched guidelines for systematically investigating contacts of persons with infectious tuberculosis (TB) in …
Article scientifique
Cost analysis of rapid diagnostics for drug-resistant tuberculosis
BACKGROUND: Growth-based drug susceptibility testing (DST) is the reference standard for diagnosing drug-resistant tuberculosis (TB), but standard time to result …
Article scientifique
Assessment of the societal cost of Taenia solium in Angónia district, Mozambique
BACKGROUND: The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease …
Article scientifique
High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia
BACKGROUND: Despite availability of effective treatment and the implementation of focused antenatal care (ANC), still the prevalence of syphilis persists …
Article scientifique
Investigation of household contacts of pulmonary tuberculosis patients increases case detection in Mwanza City, Tanzania
BACKGROUND: Tuberculosis (TB) contact tracing is a key strategy for containing TB and provides addition to the passive case finding …
Article scientifique
Assessing linkage to and retention in care among HIV patients in Uganda and identifying opportunities for health systems strengthening: a descriptive study
While antiretroviral therapy (ART) availability for HIV patients has increased dramatically in Uganda, patient linkage to and retention in care …
Article scientifique
Spoligotyping based genetic diversity of Mycobacterium tuberculosis in Ethiopia: a systematic review
BACKGROUND: Understanding the types of strains and lineages of Mycobacterium tuberculosis (M. tuberculosis) circulating in a country is of paramount …
Article scientifique
SESOTHO trial (“Switch Either near Suppression Or THOusand”) – switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa
BACKGROUND: The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on …
Article scientifique
Impact of pulsed xenon ultraviolet disinfection on surface contamination in a hospital facility’s expressed human milk feed preparation area
BACKGROUND: Expressed human milk (EHM) feed preparation areas represent a potential source of unintentional nosocomial infection. Daily disinfection of environmental …
Article scientifique
Factors affecting first month adherence due to antiretroviral therapy among HIV-positive adults at Felege Hiwot Teaching and Specialized Hospital, north-western Ethiopia; a prospective study
BACKGROUND: Non-adherence to Highly Active Antiretroviral Therapy (HAART) is one of the factors for treatment failure in human immunodeficiency virus …
Article scientifique
Poor quality data challenges conclusion and decision making: timely analysis of measles confirmed and suspected cases line list in Southern Nations Nationalities and People’s Region, Ethiopia
BACKGROUND: Measles is one of the leading causes of death among young children even though a safe and cost-effective vaccine …
Article scientifique
Evaluation of HIV-1 rapid tests and identification of alternative testing algorithms for use in Uganda
INTRODUCTION: The World Health Organization recommends that countries conduct two phase evaluations of HIV rapid tests (RTs) in order to …
Article scientifique
Performance of loop-mediated isothermal amplification assay in the diagnosis of pulmonary tuberculosis in a high prevalence TB/HIV rural setting in Uganda
BACKGROUND: Smear microscopy lacks sensitivity especially in HIV co-infection, resulting in undiagnosed tuberculosis (TB) and high mortality. The loop-mediated isothermal …
Article scientifique
Molecular characterization of mutations associated with resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients from high prevalence tuberculosis city in Morocco
BACKGROUND: The emergence of extensively drug-resistant tuberculosis (XDR-TB) has raised public health concern for global TB control. Although multi drug-resistant …
Article scientifique
Microbial contaminants isolated from items and work surfaces in the post- operative ward at Kawolo general hospital, Uganda
Nosocomial infections are a major setback in the healthcare delivery system especially in developing countries due to the limited resources. …
Article scientifique
Anemia in people on second line antiretroviral treatment in Lilongwe, Malawi: a cross-sectional study
BACKGROUND: Anemia is common among people living with HIV infection and is frequently associated with poor quality of life and …
Article scientifique
Active ingredients of a person-centred intervention for people on HIV treatment: analysis of mixed methods trial data
BACKGROUND: A new model of care is required to meet the changing needs of people living with HIV (PLWH), particularly …