710 publication(s) trouvée(s)
Article scientifique
Treating schistosomiasis among South African high school pupils in an endemic area, a qualitative study
BACKGROUND: Schistosomiasis, a neglected tropical disease caused by parasites that infest open water sources such as rivers and dams may …
Article scientifique
Risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in a tertiary armed force referral and teaching hospital, Ethiopia
BACKGROUND: Ethiopia is one of the world health organization defined higher tuberculosis (TB) burden countries where the disease remains a …
Article scientifique
Prevalence of self-reported symptoms of sexually transmitted infections, knowledge and sexual behaviour among youth in semi-rural Tanzania in the period of adolescent friendly health services strategy implementation
BACKGROUND: Global evidence shows that sexually transmitted infections (STIs) prevalence and sexual risk behaviours are high among youth, and knowledge …
Article scientifique
Faecal colonization of E. coli and Klebsiella spp. producing extended-spectrum beta-lactamases and plasmid-mediated AmpC in Mozambican university students
BACKGROUND: In recent years, the world has seen a surge in Enterobacteriaceae resistant to broad-spectrum beta-lactam antibiotics due to the …
Article scientifique
Onchocerca - infected cattle produce strong antibody responses to excretory-secretory proteins released from adult male Onchocerca ochengi worms
BACKGROUND: The front line molecules from filarial worms and other nematodes or helminthes are their Excretory-Secretory (ES) products. Their interaction …
Article scientifique
Mother-to-child transmission of HIV infection and its associated factors in Ethiopia: a systematic review and meta-analysis
Mother-to-child transmission (MTCT) is the main mode of HIV transmission in children under 15 years old. This problem is significant …
Article scientifique
Filaria specific antibody response profiling in plasma from anti-retroviral naïve Loa loa microfilaraemic HIV-1 infected people
BACKGROUND: In West and Central Africa areas of endemic Loa loa infections overlap with regions of high prevalence of human …
Article scientifique
Determinants of CD4 cell count change and time-to default from HAART; a comparison of separate and joint models
BACKGROUND: HIV has the most serious effects in Sub-Saharan African countries as compared to countries in other parts of the …
Article scientifique
Effect of an intervention targeting inappropriate continued empirical parenteral vancomycin use: a quasi-experimental study in a region of high MRSA prevalence
BACKGROUND: Despite vancomycin use is a major risk factor for the emergence of vancomycin resistance, it is frequently inappropriately prescribed, …
Article scientifique
A cross-sectional study of tuberculosis drug resistance among previously treated patients in a tertiary hospital in Accra, Ghana: public health implications of standardized regimens
BACKGROUND: Mycobacterium tuberculosis drug resistance is a major challenge to the use of standardized regimens for tuberculosis (TB) therapy, especially …
Article scientifique
Pressure ulcer-related pelvic osteomyelitis: evaluation of a two-stage surgical strategy (debridement, negative pressure therapy and flap coverage) with prolonged antimicrobial therapy
BACKGROUND: A two-stage surgical strategy (debridement-negative pressure therapy (NPT) and flap coverage) with prolonged antimicrobial therapy is usually proposed in …
Article scientifique
Population sensitivity of acute flaccid paralysis and environmental surveillance for serotype 1 poliovirus in Pakistan: an observational study
BACKGROUND: To support poliomyelitis eradication in Pakistan, environmental surveillance (ES) of wastewater has been expanded alongside surveillance for acute flaccid …
Article scientifique
Mortality and treatment response amongst HIV-infected patients 50 years and older accessing antiretroviral services in South Africa
BACKGROUND: Little is known about the clinical presentation and outcomes amongst older HIV infected populations accessing ART in sub-Saharan Africa. …
Article scientifique
Pilot evaluation of a second-generation electronic pill box for adherence to Bedaquiline and antiretroviral therapy in drug-resistant TB/HIV co-infected patients in KwaZulu-Natal, South Africa
BACKGROUND: The introduction of Bedaquiline, the first new antimycobacterial drug in over 40 years, has highlighted the critical importance of …
Article scientifique
The magnitude of antibiotic resistance to Helicobacter pylori in Africa and identified mutations which confer resistance to antibiotics: systematic review and meta-analysis
BACKGROUND: Worldwide Helicobacter pylori (H.pylori) treatment is of great challenge due to increased antibiotic resistance. The burden of H. pylori …
Article scientifique
Increasing nontuberculous mycobacteria reporting rates and species diversity identified in clinical laboratory reports
BACKGROUND: Nontuberculous Mycobacteria (NTM) are environmental microorganisms that can affect human health. A 2009-2010 occurrence survey of NTM in potable …
Article scientifique
Characteristics of human encounters and social mixing patterns relevant to infectious diseases spread by close contact: a survey in Southwest Uganda
BACKGROUND: Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet …
Article scientifique
Factors affecting adherence to antiretroviral therapy among pregnant women in the Eastern Cape, South Africa
BACKGROUND: Context-specific factors influence adherence to antiretroviral therapy (ART) among pregnant women living with HIV. Gaps exist in the understanding …
Article scientifique
Mycobacterium tuberculosis thymidylate kinase antigen assays for designating incipient, high-risk latent M.tb infection
BACKGROUND: Precise designation of high risk forms of latent Mycobacterium tuberculosis-M.tb infections (LTBI) is impossible. Delineation of high-risk LTBI can, …
Article scientifique
Household contact non-attendance of clinical evaluation for tuberculosis: a pilot study in a high burden district in South Africa
BACKGROUND: In 2012, the World Health Organization launched guidelines for systematically investigating contacts of persons with infectious tuberculosis (TB) in …