663 publication(s) trouvée(s)
Article scientifique
Benefits of annual chemotherapeutic control of schistosomiasis on the development of protective immunity
BACKGROUND: Schistosomiasis is a devastating parasitic disease. The mainstay of schistosomiasis control is by praziquantel treatment. The study aimed to …
Article scientifique
Magnitude and correlates of virological failure among adult HIV patients receiving PI based second line ART regimens in north western Tanzania; a case control study
BACKGROUND: With a growing access to free ART, switching of ART to second line regimen has also become common following …
Article scientifique
Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa
We assessed the utility of a multi-target, real-time PCR assay for Bordetella pertussis detection and diagnosis in patients with severe …
Article scientifique
Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with Trichuris trichiura: study protocol for a multi-country randomized controlled double-blind trial
BACKGROUND: Soil-transmitted helminthiasis affects almost 2 billion people worldwide in tropical climates. Preventive chemotherapy, using the benzimidazoles (albendazole and mebendazole) …
Article scientifique
HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon
With the phase-out of stavudine (d4T), change to first-line regimens with zidovudine (AZT) or tenofovir (TDF) in resource-limited settings (RLS) …
Article scientifique
Exploring the complex relationship between women’s sanitation practices and household diarrhea in the slums of Nairobi: a cross-sectional study
BACKGROUND: Diarrheal disease kills over half a million people each year in sub-Saharan Africa; the majority are children under 5 …
Article scientifique
Health providers’ experiences, perceptions and readiness to provide HIV services to men who have sex with men and female sex workers in Uganda – a qualitative study
BACKGROUND: Access to HIV services among men who have sex with men (MSM) and female sex workers (FSWs) remains suboptimal …
Article scientifique
Stigma and outness about sexual behaviors among cisgender men who have sex with men and transgender women in Eswatini: a latent class analysis
BACKGROUND: Men who have sex with men (MSM) and transgender women in Sub-Saharan Africa are subjected to high levels of …
Article scientifique
Incidence and predictors of major adverse drug events among drug-resistant tuberculosis patients on second-line anti-tuberculosis treatment in Amhara regional state public hospitals; Ethiopia: a retrospective cohort study
BACKGROUND: Second line anti-tuberculosis drugs are substantially complex, long term, more costly, and more toxic than first line anti-tuberculosis drugs. …
Article scientifique
The role of super-spreading events in Mycobacterium tuberculosis transmission: evidence from contact tracing
BACKGROUND: In current epidemiology of tuberculosis (TB), heterogeneity in infectiousness among TB patients is a challenge, which is not well …
Article scientifique
Prevalence, predictors, and management of advanced HIV disease among individuals initiating ART in Senegal, West Africa
The WHO guidelines for the management of advanced HIV disease recommend a package of care consisting of rapid initiation of …
Article scientifique
Apparent overuse of antibiotics in the management of watery diarrhoea in children in Abakaliki, Nigeria
BACKGROUND: Diarrhoea remains an important cause of childhood mortality in Nigeria, with Rotavirus and Cryptosporidium reported to have the highest …
Article scientifique
Current status of intestinal parasitic infections and associated factors among primary school children in Birbir town, Southern Ethiopia
BACKGROUND: Intestinal parasites still pose major public health problems in developing countries like Ethiopia. Local epidemiological data is indispensable in …
Article scientifique
Prevalence of diabetes mellitus among tuberculosis patients in Sub-Saharan Africa: a systematic review and meta-analysis of observational studies
Tuberculosis and diabetes mellitus are significant global public health challenges. In Sub-Saharan Africa, study findings regarding prevalence of diabetes mellitus …
Article scientifique
Hepatitis B virus sero-prevalence amongst pregnant women in the Gambia
BACKGROUND: Infection with Hepatitis B virus (HBV) is a serious public health problem worldwide, with over 360 million carriers. Sixty …
Article scientifique
Correction to: Association of HIV-infection, antiretroviral treatment and metabolic syndrome with large artery stiffness: a cross-sectional study
Following publication of the original article [1], the authors reported that they have provided the wrong caption.
Article scientifique
A comparative cross-sectional study of prevalence and intensity of soil-transmitted helminthic infection between healthy and severe acutely malnourished pre-school aged children in Kano, Northern Nigeria
BACKGROUND: Soil-transmitted helminthic (STH) infections are common in Sub-Saharan Africa. One method used for control of these helminths is mass …
Article scientifique
Predictors of discordant latent tuberculosis infection test results amongst South African health care workers
BACKGROUND: The tuberculin skin test (TST) and interferon-gamma-release-assays (IGRAs) are utilized in screening programmes for presumed latent tuberculosis infection (LTBI) …
Article scientifique
Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis
BACKGROUND: Empirical treatment of tuberculosis (TB) may be necessary in patients with negative or no Xpert MTB/RIF results. In a …
Article scientifique
Pooled PCR testing of dried blood spots for infant HIV diagnosis is cost efficient and accurate
BACKGROUND: Access to qualitative HIV PCRs for early infant diagnosis (EID) is restricted in resource-limited settings due to cost. We …