155 publication(s) trouvée(s)
Article scientifique
Inhibition of lipopolysaccharide (LPS)-induced neuroinflammatory response by polysaccharide fractions of Khaya grandifoliola (C.D.C.) stem bark, Cryptolepis sanguinolenta (Lindl.) Schltr and Cymbopogon citratus Stapf leaves in raw 264.7 macrophages and U87 glioblastoma cells
BACKGROUND: Khaya grandifoliola (C.D.C.) stem bark, Cymbopogon citratus (Stapf) and Cryptolepis sanguinolenta (Lindl.) Schltr leaves are used in Cameroonian traditional …
Article scientifique
Rhaponticum acaule (L) DC essential oil: chemical composition, in vitro antioxidant and enzyme inhibition properties
BACKGROUND: α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments …
Article scientifique
Prevalence and correlates of herbal medicine use among type 2 diabetic patients in Teaching Hospital in Ethiopia: a cross-sectional study
BACKGROUND: Type 2 Diabetes Mellitus (T2DM) patients are increasingly using herbal remedies due to the fact that sticking to the …
Article scientifique
South African medicinal plant extracts active against influenza A virus
Influenza infection remains a major health threat for animals and humans which crucially requires effective antiviral remedies. The usage of …
Article scientifique
Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells
Most of herbal medicines are used without any standard safety and toxicological trials although common assumption is that these products …
Article scientifique
In vitro antileishmanial and cytotoxicity activities of essential oils from Haplophyllum tuberculatum A. Juss leaves, stems and aerial parts
Plants used for traditional medicine produce diverse and complex secondary metabolites exhibiting various medicinal properties. The medicinal plant Haplophyllum tuberculatum …
Article scientifique
Anti-aging potential of extracts from Sclerocarya birrea (A. Rich.) Hochst and its chemical profiling by UPLC-Q-TOF-MS
BACKGROUND: Degradation of components of the extracellular matrix such as elastin and collagen by elastase and collagenase accelerates skin aging. …
Article scientifique
Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
BACKGROUND: Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. …
Article scientifique
Phytochemical analysis, antioxidant and anti-inflammatory potential of FERETIA APODANTHERA root bark extracts
BACKGROUND: Inflammation has been implicated in many disorders, including cancer and available therapies elicit adverse effects. Plants of the family …
Article scientifique
In vitro antibacterial and antibiotic modifying activity of crude extract, fractions and 3′,4′,7-trihydroxyflavone from Myristica fragrans Houtt against MDR Gram-negative enteric bacteria
BACKGROUND: Nutmeg is the seed kernel inside the fruit of Myristica fragrans Houtt. (Myristicaceae). It possesses various pharmacological activities but …
Article scientifique
Correction to: Ficus sycomorus extract reversed behavioral impairment and brain oxidative stress induced by unpredictable chronic mild stress in rats
Correction After the publication of this article [1] it came to our attention that Harquin Simplice Foyet was incorrectly included …
Article scientifique
Anti-diabetic potential of Sapium ellipticum (Hochst) Pax leaf extract in Streptozotocin(STZ)-induced diabetic Wistar rats
BACKGOUND: Ethnobatanical survey associates Sapium ellipticum (SE) with antidiabetic usage among other medicinal functions in different parts of Africa. More …
Article scientifique
Anti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil
BACKGROUND: Mood disorder accounts for 13 % of global disease burden. And while therapeutic agents are available, usually orally administered, …
Article scientifique
The immunomodulatory activities of licorice polysaccharides (Glycyrrhiza uralensis Fisch.) in CT 26 tumor-bearing mice
BACKGROUND: The increasing use of complementary and alternative medicine (CAM) has kindled the need for scientific evaluation of the mechanism …
Article scientifique
A putative Chondroprotective role for IL-1β and MPO in herbal treatment of experimental osteoarthritis
BACKGROUND: Herbal treatment may have a chondroprotective and therapeutic effect on Osteoarthritis (OA). We investigated the mechanism of action of …
Article scientifique
Ficus sycomorus extract reversed behavioral impairment and brain oxidative stress induced by unpredictable chronic mild stress in rats
Stress, regardless of its nature is nowadays recognized as one of the major risk factors for neuropsychiatric diseases, such as …
Article scientifique
Integrating herbal medicine into mainstream healthcare in Ghana: clients’ acceptability, perceptions and disclosure of use
BACKGROUND: Although there are current efforts to integrate herbal medicine (HM) into mainstream healthcare in Ghana, there is paucity of …
Article scientifique
In vitro cytotoxic activity of medicinal plants from Nigeria ethnomedicine on Rhabdomyosarcoma cancer cell line and HPLC analysis of active extracts
BACKGROUND: Cancer is a leading cause of death world-wide, with approximately 17.5 million new cases and 8.7 million cancer related …
Article scientifique
Defatting of acetone leaf extract of Acacia karroo (Hayne) enhances its hypoglycaemic potential
BACKGROUND: Conventional drugs used to treat diabetes are too expensive, toxic and rarely available to rural communities. This study was …
Article scientifique
Bidens pilosa Ethylene acetate extract can protect against L-NAME-induced hypertension on rats
BACKGROUND: Essential hypertension is mainly caused by endothelial dysfunction which results from nitric oxide (NO) deficiency. The present study was …