121 publication(s) trouvée(s)
Article scientifique
Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment
BACKGROUND: Accelerated malignant behaviors induced by insufficient thermal ablation have been increasingly reported, however, the exact mechanisms are still unclear. …
Article scientifique
EGFR mutation frequency in Middle East and African non-small cell lung cancer patients: a systematic review and meta-analysis
BACKGROUND: Our goal was to investigate the prevalence of the epidermal growth factor receptor (EGFR) mutation in Middle East and …
Article scientifique
Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients
BACKGROUND: Oxidative stress induces various intracellular damage, which might be correlated with tumorigenesis. Accumulated oxidative stresses might inactivate protein tyrosine …
Article scientifique
MRI in predicting the response of gastrointestinal stromal tumor to targeted therapy: a patient-based multi-parameter study
BACKGROUND: To investigate the performance of quantitative indicators of MRI in early prediction of the response of gastrointestinal stromal tumor …
Article scientifique
Liver cancer mortality trends in South Africa: 1999–2015
BACKGROUND: In South Africa (SA), liver cancer (LC) is a public health problem and information is limited. METHODS: Joinpoint regression …
Article scientifique
Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes
BACKGROUND: Colorectal cancer (CRC) remains a leading cause of death worldwide. Utilizing cisplatin in CRC is correlated with severe adverse …
Article scientifique
Outcome of inflammatory breast cancer in Moroccan patients: clinical, molecular and pathological characteristics of 219 cases from the National Oncology Institute (INO)
BACKGROUND: Usually misdiagnosed, Inflammatory Breast Cancer (IBC) is the most aggressive form of non-metastatic breast cancer. This orphan disease is …
Article scientifique
Targeting HOX-PBX interactions causes death in oral potentially malignant and squamous carcinoma cells but not normal oral keratinocytes
BACKGROUND: High HOX gene expression has been described in many cancers, including oral squamous cell carcinoma and the functional roles …
Article scientifique
Incidence and risk factors of subsyndromal delirium after curative resection of gastric cancer
BACKGROUND: Subsyndromal delirium, a condition in which patients exhibit some, but not all, of the symptoms of delirium, can negatively …
Article scientifique
Women’s knowledge and attitudes related to cervical cancer and cervical cancer screening in Isiolo and Tharaka Nithi counties, Kenya: a cross-sectional study
BACKGROUND: Cervical cancer is the most common cancer among women in Kenya. However, only 3% of women are routinely screened. …
Article scientifique
Low expression of RECQL is associated with poor prognosis in Chinese breast cancer patients
BACKGROUND: RECQL is a number of the RecQ DNA helicase family and plays an important role in maintaining genome stability. …
Article scientifique
Survival after the diagnosis of breast or colorectal cancer in the GAZA Strip from 2005 to 2014
BACKGROUND: Within a dramatic socio-political context, cancer represents a growing health burden in the Gaza Strip. We investigated the survival …
Article scientifique
Trends in pancreatic adenocarcinoma incidence and mortality in the United States in the last four decades; a SEER-based study
BACKGROUND: Pancreatic cancer is the fourth-leading cause of cancer deaths in the United States. The silent nature of the disease …
Article scientifique
Telomere length differences between colorectal polyp subtypes: a colonoscopy-based case-control study
BACKGROUND: Short telomeres have been associated with increased risk of many cancers, particularly cancers of the gastrointestinal tract including esophagus …
Article scientifique
Vemurafenib in Chinese patients with BRAFV600 mutation–positive unresectable or metastatic melanoma: an open-label, multicenter phase I study
BACKGROUND: kinase approved in more than 90 countries, based on results obtained primarily in Caucasian patients. Limited data are available …
Article scientifique
Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population
BACKGROUND: Several studies have reported the role of CYP2A6 genetic polymorphisms in smoking and lung cancer risk with some contradictory …
Article scientifique
Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation
BACKGROUND: Cancer remains one of the leading causes of death around the world, where incidence and mortality rates are at …
Article scientifique
Uptake of three doses of HPV vaccine by primary school girls in Eldoret, Kenya; a prospective cohort study in a malaria endemic setting
BACKGROUND: All women are potentially at risk of developing cervical cancer at some point in their life, yet it is …
Article scientifique
PDXliver: a database of liver cancer patient derived xenograft mouse models
BACKGROUND: Liver cancer is the second leading cause of cancer-related deaths and characterized by heterogeneity and drug resistance. Patient-derived xenograft …
Article scientifique
Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures
BACKGROUND: There is increasing appreciation that non-cancer cells within the tumour microenvironment influence cancer progression and anti-cancer drug efficacy. For …