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Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population

Article scientifique 2017 Anglais

Résumé

OBJECTIVE: To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. RESULTS: Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic's 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution.

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Munang, Y., Noubiap, J., Danwang, C., Sama, J., Azabji‐Kenfack, M., Mbanya, J., Sobngwi, E. (2017). Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population. https://doi.org/10.1186/s13104-017-2944-7

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Auteur(s)

Yvonne Nangeh Munang Jean Jacques Noubiap Célestin Danwang Julius Dohbit Sama Marcel Azabji‐Kenfack Jean Claude Mbanya Eugène Sobngwi

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