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SARS-CoV-2 Vaccine Breakthrough Infections and the Assessment of Pre and Post- vaccination Attitude among Healthcare Workers towards the Practice of Safety Precautions in South West, Nigeria

Article scientifique 2023 Anglais

Résumé

Abstract Introduction Worldwide, it has been reported that fully vaccinated people still died of COVID-19-associated symptoms, generating public uncertainty about the safety and effectiveness of the vaccines. Hence, this research is aimed at assessing the incidence of COVID-19 breakthrough infection among vaccinated Health Workers and the possible effect of changes in the practice of post-vaccination safety precautions. Method This was a Health facility-based descriptive cross-sectional study. Data were collected using self-administered questionnaires distributed at the participant’s work unit across the selected health facilities. The nasopharyngeal specimen was also obtained from the participants and analysed using STANDARD Q COVID-19 Ag Test rapid chromatographic immunoassay for the detection of antigens to SARS-CoV-2. All data were input and analyzed using SPSS version 20. Results There was a statistically significant relationship between the vaccination status of respondents and the post-vaccination test result (χ2 = 6.816, df =1, p= 0.009). The incidence of covid-19 infection among the vaccinated and unvaccinated HCWs was 2 % and 8 % respectively. 5 of the 15 respondents who tested positive for covid-19 had been fully vaccinated. However, all 5 of them did not practice safety measures after vaccination. None of the respondents who practised safety measures after vaccination tested positive for covid-19. The remaining 10 respondents that tested positive for covid-19 had not been vaccinated though they practised safety precautions. Conclusion Vaccination and the practice of safety precautions will go a long way to preventing future Covid-19 breakthrough infections.

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Oni, O., Osho, P., Odesanmi, T., Raji, H., Ojo, F., Ibina, D. (2023). SARS-CoV-2 Vaccine Breakthrough Infections and the Assessment of Pre and Post- vaccination Attitude among Healthcare Workers towards the Practice of Safety Precautions in South West, Nigeria. https://doi.org/10.21203/rs.3.rs-3179536/v1

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Auteur(s)

Oluwatosin Oni Oni Patrick Olanrewaju Osho Tayelolu Mary Odesanmi Habeebat Motunrayo Raji Faith T. Ojo Demian Ibina

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