Ethyl tetratriacontanoate and non-polar compounds from Mitragyna inermisstem bark

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Abstract Mitragyna inermis is widely reported for its biological activities and phytochemical components. In this report, we investigated, the non-polar compounds from stem bark by thin layer chromatography and GC-MS analysis. The thin layer chromatography on DCM fraction yielded ethyl tetratriacontanoate (1’). That compound is on the first isolation from M. inermis. Besides, gas chromatography allowed identification of thirteen major compounds as well as alkanes, phytol, esters, ester-alcohol, carboxylic acids, ester-carboxylic acids and cyanate. All compounds are on the first report on M. inermis and most are fatty acids and essential oils. These compounds might contribute to stem potent antioxidant, antidiabetic and antimicrobial effects. Further investigation for drug research with these non-polar compounds might allow to know their specific activities.

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