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Bis (2-Cyanoacetohydrazide) as Precursors for Synthesis of Novel Azoles / Azines and their Biological Evaluation

Article scientifique 2022 Anglais

Résumé

Abstract The present work deals with the synthesis of 2-cyano-N'-(3-(2-(2-cyanoacetyl) hydrazinyl) cyclohex-2-en-1-ylidene) acetohydrazide 3 that used as a key precursor in the manufacture of new heterocyclic derivatives, such as pyrazole, pyrane, pyridine and pyrole incorporating cyclohexene moiety via its reaction with a variety of nucleophilic and electrophilic reagents. The newly synthesized compounds were characterized by their elemental analyses (IR, 1H-NMR, 13C-NMR and Mass spectra) and assessed for their anti-microbial activity.

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Sophy, M., Reheim, M. (2022). Bis (2-Cyanoacetohydrazide) as Precursors for Synthesis of Novel Azoles / Azines and their Biological Evaluation. https://doi.org/10.21203/rs.3.rs-2327892/v1

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