Accès ouvert

A hidden burden of disease in a specific group: Evaluation of COVID-19 seroconversion rates in pediatric patients with leukemia

Article scientifique 2022 Anglais

Résumé

Abstract Background SARS-CoV-2, a respiratory viral disease, is thought to have a more severe course in patients with malignancy and low immune systems. Methods This prospective single-center study was conducted at the University of Health Sciences Dr. Behçet Uz Children's Hospital from September 22 and December 31, 2021. Asymptomatic COVID-19 transmission rates were assessed using SARS-CoV-2 serology in patients with leukemia who had no history of COVID-19 infection. Results Among the 54 patients, 19 (35.2%) were females and 35 (64.8%) were males. The median age was 5.5 years (min 6 months, max 17 years). Forty-nine (90.5%) of the leukemia patients had acute lymphoblastic leukemia (ALL), while 5 (9.5%) had acute myeloid leukemia (AML). Five of the 54 patients had a history of COVID-19 or contact with a positive person. SARS-CoV-2 IgG positivity was detected in 18 (36.7%) of 49 patients with no history of COVID-19 infection. Discussion Leukemia patients have a high seroconversion for SARS-CoV-2 without showing any symptoms supporting the asymptomatic course of COVID-19 infection in this risk group.

Citer ce document

Çelebi, M., Şahinkaya, Ş., Cem, E., Kara, A., Özdağ, E., Ayhan, F., Karakaya, N., Al, I., Gözmen, S., Karapınar, T., Oymak, Y., Bayram, N., Devrim, İ. (2022). A hidden burden of disease in a specific group: Evaluation of COVID-19 seroconversion rates in pediatric patients with leukemia. https://doi.org/10.21203/rs.3.rs-2283213/v1

Accès au document

Voir sur le dépôt source

Ce document est hébergé sur son dépôt institutionnel d'origine.

Auteur(s)

Miray Yılmaz Çelebi Şahika Şahinkaya Ela Cem Aybüke Akaslan Kara Eda Özdağ Fahri Yüce Ayhan Nurgül Karakaya Işık Odaman Al Salih Gözmen Tuba Hilkay Karapınar Yeşim Oymak Nuri Bayram İlker Devrim

Statistiques

Consultations : 1

Téléchargements : 0