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Diagnosis of Immunoglobulin D myeloma with severe renal involvement ten years after a solitary plasmacytoma

Article scientifique 2023 Anglais

Résumé

Abstract Immunoglobulin D myeloma is a rare subtype often described as aggressive with advanced disease at diagnosis. Primary renal involvement is seen in scarce cases. The aim of the present study was to describe the case of a 55‑year‑old male patient with immunoglobulin D‑λ myeloma who presented with severe renal failure at diagnosis. On examination, he presented a 10- year-old sternal arch. Investigations concluded a sternal plasmacytoma associated with multiple others in the ribs. He benefited from traditional chemotherapy and remained hemodialysis-dependent. We concluded that IgD-secreting plasma cells could remain quiescent for a long time in the form of a solitary plasmacytoma. However, in case of bone marrow involvement, they may induce myeloma with serious organic damage.

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Mrabet, S., Hmida, M. (2023). Diagnosis of Immunoglobulin D myeloma with severe renal involvement ten years after a solitary plasmacytoma. https://doi.org/10.21203/rs.3.rs-2868593/v1

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Auteur(s)

Sanda Mrabet M. Ben Hmida

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