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Correlation Between Cyclin D1 Expression With Different Pathological Changes in Colorectum Patients

Article scientifique 2022 Anglais

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Abstract Background: Cyclin D1 plays a vital role in cancer cell cycle progression and is overexpressed in many human cancers, including colorectal cancer. Objectives:This study was aimed to detect cyclin D1 in colorectal cancer patients and to correlate cyclin D1 expression with different pathological changes in colorectum.Methods: Tissues microarray paraffin block with 48 colorectal cancer samples were retrieved from the archives of Elrahma Medical Center. The cyclin D1 was analyzed.Results:Cyclin D1 did not correlate with pathological alterations and with tumor grade.Conclusion:Results indicated that; cyclin D1 not correlates with pathological alteration of colorectal cancer.

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Mohammed, H., Elsheikh, M., Idris, A. (2022). Correlation Between Cyclin D1 Expression With Different Pathological Changes in Colorectum Patients. https://doi.org/10.21203/rs.3.rs-1220462/v1

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Hanaa Ibrahim Salih Mohammed Mohammed Abdelgader Elsheikh Alkhair Abd Almahmoud Idris

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