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Cohort Profile: The Adverse Childhood Experiences (ACE) Cohort of the Malawi Longitudinal Study of Families and Health (MLSFH)

Article scientifique 2023 Anglais

Résumé

Purpose: The Adverse Childhood Experiences cohort of the Malawi Longitudinal Study of Fami-lies and Health (MLSFH-ACE) is a study of adolescents created during 2017-21. It provides un-paralleled opportunity to examine the longitudinal impact of adverse childhood experiences on health and development across the early life course. The MLSFH-ACE cohort provides rich data on adolescents, their children, and adult caregivers in a low-income, high HIV prevalence context in sub-Saharan African (SSA).Participants: The MLSFH-ACE cohort is a population-based cohort of adolescents living in three districts in rural Malawi. Wave 1 enrollment took place in 2017-2018 and included 2061 adoles-cents aged 10-16 years and 1438 caregivers. Wave 2 took place in 2021 and included data on 1878 adolescents and 208 offspring. Survey instruments captured ACEs during childhood and adolescence, HIV-related behavioral risk, mental and physical health, cognitive development and education, intimate partner violence (IPV), marriage and aspirations, early transitions to adult-hood, and protective factors. Biological indicators included HIV, HSV2, and anthropometric measurements.Findings to date: Key findings include a high prevalence of ACEs among adolescence in Mala-wi, a low incidence of HIV, and positive associations between ACEs scores and composite HIV risk scores. There were also strong associations between ACEs and both IPV victimization and perpetration.Future plans: MLSFH-ACE data will be publicly released and will provide a wealth of information on ACEs and adolescent outcomes in low-income, HIV-endemic SSA context. Future expansions of the cohort are planned to capture data during early adulthood.

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Kidman, R., Mwera, J., Yang, R., Breton, E., Zulu, A., Behrman, J., Kohler, H. (2023). Cohort Profile: The Adverse Childhood Experiences (ACE) Cohort of the Malawi Longitudinal Study of Families and Health (MLSFH). https://doi.org/10.31235/osf.io/gru6e

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Auteur(s)

Rachel C. Kidman James Mwera Rui Yang Etienne Breton Andrew Zulu Jere R. Behrman Hans‐Peter Kohler

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