Timing and cause of perinatal mortality for small-for-gestational-age babies in South Africa: critical periods and challenges with detection

Résumé

BACKGROUND: Little information exists on timing and cause of death for small-for-gestational-age (SGA) babies in low-and-middle-income-countries (LMICs), despite evidence from high-income countries suggesting critical periods for SGA babies. This study explored the timing and cause of stillbirth and early neonatal mortality (END, <7 days) by small-for-gestational age in three provinces in South Africa. In South Africa, the largest category of perinatal deaths is unexplained stillbirth, of which up to one-quarter have intra-uterine growth restriction. METHODS: Secondary analysis of the South African Perinatal Problems Identification Program (PPIP) database allowed for the analysis of gestational age at death and clinically confirmed diagnosis of stillbirth and early neonatal death (END) (>1000 g and >28 weeks) across gestation. Comparisons by province, size-for-gestational-age, gestational age groups, and maternal condition at death were performed. The provinces investigated were: Western Cape (fortnightly antenatal care visits from 32 to 38 weeks), Limpopo and Mpumalanga (no antenatal care visits between 32 to 38 weeks). RESULTS: < 0.05). No increase was seen in poor maternal condition for SGA babies and 54.9 % of deaths had a healthy mother. Of mothers that were healthy the greatest proportion of SGA stillbirths were due to unexplained intrauterine death (53.9 %). CONCLUSION: There was a peak in stillbirths for SGA babies 33-37 weeks in all provinces. Detecting SGA is further complicated as in most cases the mother is healthy. Further research into Umbiflow Doppler velocimetry use in low-risk populations is warranted and may be a viable strategy to increase current detection of SGA babies at risk of mortality in LMICs.

Citer ce document

Accès au document

Ce document est hébergé sur son dépôt institutionnel d'origine.

Auteur(s)

Statistiques

Consultations : 3

Téléchargements : 0