The effectiveness of platelet-rich plasma on the skin wound healing process: A comparative experimental study in sheep
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AIM: The therapeutic evaluation of the biological effect of platelet-rich plasma (PRP) used as a surgical adjunct to maintain the inflammatory process and to potentiate tissue healing, make the subject of recent research in regenerative medicine. This study was designed to evaluate the healing activity of PRP by its topical application on the skin experimentally injured in a sheep model. MATERIALS AND METHODS: days of healing. RESULTS: day of healing in favor for animals of Group I. Semi-quantitative histopathological evaluation showed that PRP reduces inflammation during 3 first days post-surgical and promotes epithelialization in 3 weeks of healing. CONCLUSION: We concluded that topical administration of PRP obtained by double centrifugation protocol could potentially improve the skin healing process in sheep.
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