Review of: "Design and Molecular Screening of Various Compounds by Molecular Docking as BACE-1 Inhibitors"
Résumé
Reviewer commentIn this study, the authors use molecular docking to study the interaction of quercetin, myricetin, & baicalein, ferulic acid, and donepezil with the BACE-1 protein and found that these compounds exhibit binding affinity, showing that they can fit better in the active site of BACE-1.According to the authors, these findings represent a major breakthrough in Alzheimer's disease research.This paper appears to be interesting but needs a major revision.It cannot be accepted in its current form; therefore, further corrections are required following the comments listed below :1.In the introduction, I understand that the authors want to clarify the β-amyloid hypothesis by using the colon; I would
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