Prevalence of Helicobacter Pylori Among Sudanese Patients Diagnosed with Colon Polyps and Colon Cancer using Immunohistochemistry Technique.

Résumé

Abstract Objectives: infection with the bacteria Helicobacter pylori has been classified as class 1 carcinogen associated with increasing susceptibility of gastritis and gastric carcinoma. This study is aiming at investigating the prevalence of H. pylori in colon polyps and colon cancer lesions. A descriptive cross-sectional hospital-based study was conducted between February and June 2017. Sixty-nine formalin fixed paraffin blocks from colon polyps and colon cancer lesions to detect H. pylori using immunohistochemistry technique.Results: Of the Sixty-nine patients included in the study, 39 (56.5%) males and 30 (43.5%) were females, their age ranged from 21 to 80 years with a mean age of 47.1 ± 19.7. Of the 69 colon polyps and colon cancer cases, 44 (63.8%) were diagnosed as adenocarcinoma, 10 (14.5%) colitis, 15 (21.7%) juvenile polyposis syndrome. The results of immunohistochemistry technique showed the presence of 16 (23.2%) positive patients for H. pylori infection. Of these 16, 13 (81.3%) patients were off those diagnosed with adenocarcinoma and the remaining 3 (18.7%) patients were diagnosed with juvenile polyps. the results of H. pylori detection among the different colon polyps and colon cancer diagnosis was showing a statistically significant association for H. pylori infection and adenocarcinoma, P value 0.028.

Citer ce document

Accès au document

Ce document est hébergé sur son dépôt institutionnel d'origine.

Auteur(s)

Statistiques

Consultations : 1

Téléchargements : 0