Editorial: Glucocorticoids and cognition: recent advances in understanding their interaction, with a particular focus on clinical applicability for the treating endocrinologist
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Glucocorticoids and cognition: recent advances in understanding their interaction, with a particular focus on clinical applicability for the treating endocrinologistWe assembled a compendium of reviews for the Research Topic, Glucocorticoids and cognition which the reader should find both interesting and useful.Our focus was to elicit clinical applicability for the treating Endocrinologist.Throughout our lives we encounter stress of varying degrees and James et al., described stress as a general adaptation syndrome, consisting of an initial shock phase and an alarm reaction, followed by adaptation to the stressor and a phase of exhaustion.It is during the exhaustion phase that an unwanted negative stimulus can impact the individual's ability to resist the stressor.Notably, stressors may be acute or chronic in presentation.The sympathetic adrenal medullary system and the hypothalamic pituitary adrenal axis are two critical physiological systems, which respond to stressful conditions and address coping.Excessive cortisol concentrations can result in alterations in the structure and Frontiers in Endocrinology frontiersin.
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