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PfRH5 vaccine; from the bench to the vial

Article scientifique 2025 Anglais

Résumé

The search for potent malaria vaccine candidate has seen several twists and turns. Here, we provide a perspective on the current state of PfRH5-based malaria vaccine development, the progress, existing challenges, and future research directions. We discuss the clinical trials in endemic regions, immune correlates of protection, prospects of integrating PfRH5 into multi-antigen vaccine strategies and considerations on the onward development/deployment of PfRH5 vaccine from the laboratory to endemic communities.

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Ilani, P., Nyarko, P., Camara, A., Amenga–Etego, L., Aniweh, Y. (2025). PfRH5 vaccine; from the bench to the vial. https://doi.org/10.1038/s41541-025-01137-6

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Auteur(s)

Philip Ilani Prince Nyarko Abdouramane Camara Lucas Amenga–Etego Yaw Aniweh

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