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Dispensing patterns of antimigraine agents with a focus on seasonal variations in prescribing

Article scientifique 2018 Anglais

Résumé

Purpose: To determine the dispensing patterns of antimigraine agents in a private healthcare setting, focusing on seasonal variations in prescribing.Methods: A retrospective, cross-sectional drug utilization study was conducted using a South African medical insurance scheme administrator database for 2016. The database contained 3 567 170 records for medicines, medical devices and procedures. All products in MIMS category 1.9 (antimigraine agents) were analysed.Results: A total of 914 antimigraine products were dispensed to 505 patients (69.70 % females) at a cost of US$10,988.63. The average age of patients was 41.57 (SD = 13.77) years. Of the eight active ingredients, clonidine was the most often dispensed (34.68 %), followed by rizatriptan (28.01 %) and ergotamine (26.04 %). Prescribing peaks were observed in February to April 2016, and again in October. These months coincide with the change in seasons to winter and to summer, respectively, in South Africa.Conclusion: The sample size was too small to make definite conclusions, but it seems that prescribing of antimigraine agents reaches a peak during seasonal change specifically autumn and spring, confirming that weather is a possible trigger factor in migraine.Keywords: Migraine, Antimigraine agents, Trigger factors, Environmental, Weather, Seasonal, Prescribing patterns, Rizatriptan

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Truter, I., Louwrens, B., Kotze, T. (2018). Dispensing patterns of antimigraine agents with a focus on seasonal variations in prescribing. https://doi.org/10.4314/tjpr.v17i7.30

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