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Long Duration and Resurgence of SARS-CoV-2 in Cameroonian Population

Article scientifique 2021 Anglais

Résumé

Abstract BackgroundInfection with SARS-CoV-2 can lead to a detectable serological immune response even though extent of its protection is still not yet well known. We report long duration and resurgence of SARS-CoV-2 in patients with COVID-19. MethodsWe included a cohort of 99 participants from our non-blinded non-randomized evaluation of COVID-19 tests in Cameroon. Demographic and clinical information was collected from participants including self-reported age, race, ethnicity, and gender. Qualitative data was described as proportions while quantitative data was described with means and accompanying ranges.ResultsDuration of PCR for SARS-CoV-2 positivity was found to range from 4 – 81 days, with mean duration of 32.8 days in patients with PCR-positive. We also identified 4 participants who also had SARS-CoV-2 resurgence within a three-month period. ConclusionThese observations raise questions on clinical decision to release COVID-19 cases from isolation after 14 days.

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Buri, D., Matchim, L., Akendji, B., Eteki, L., Fouda, N., Bebbel, L., Ndifon, M., Hamadou, A., Dora, T., Nicolay, B., Abbah, A., Tchoula, C., Kameni, B., René, E., Nsaibirni, R., Ntonè, R., Fanne, M., Eyangoh, S., Ouamba, J., Koku, M., Mandeng, N., Esso, L., Claire, O., Epée, E., Mballa, G., Njouom, R., Boum, Y. (2021). Long Duration and Resurgence of SARS-CoV-2 in Cameroonian Population. https://doi.org/10.21203/rs.3.rs-156679/v1

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Auteur(s)

Donald Buri Lucrèce Matchim Blaise Akendji Lucrèce Eteki Nicole Mbarga Fouda Lisa Bebbel Mark Ndifon Achta Hamadou Tchiasso Dora Birgit Nicolay Aristide Abbah Corinne M. Tchoula Bertrand Tchualeu Kameni Essomba René Robert Nsaibirni Rodrigue Ntonè Mahamat Fanne Sara Eyangoh Jean Patrick Ouamba Modeste Tamakloé Koku Nadia Mandeng Linda Esso Okomo Marie Claire Emilienne Epée Georges Alain Etoundi Mballa Richard Njouom Yap Boum

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