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Perceived COVID-19 vaccine effectiveness, acceptance, and drivers of vaccination decision-making among the general adult population: A global survey of 20 countries

Article scientifique 2022 Anglais

Résumé

BACKGROUND: Mass vaccination campaigns have significantly reduced the COVID-19 burden. However, vaccine hesitancy has posed significant global concerns. The purpose of this study was to determine the characteristics that influence perceptions of COVID-19 vaccine efficacy, acceptability, hesitancy and decision making to take vaccine among general adult populations in a variety of socioeconomic and cultural contexts. METHODS: Using a snowball sampling approach, we conducted an online cross-sectional study in 20 countries across four continents from February to May 2021. RESULTS: A total of 10,477 participants were included in the analyses with a mean age of 36±14.3 years. The findings revealed the prevalence of perceptions towards COVID-19 vaccine's effectiveness (78.8%), acceptance (81.8%), hesitancy (47.2%), and drivers of vaccination decision-making (convenience [73.3%], health providers' advice [81.8%], and costs [57.0%]). The county-wise distribution included effectiveness (67.8-95.9%; 67.8% in Egypt to 95.9% in Malaysia), acceptance (64.7-96.0%; 64.7% in Australia to 96.0% in Malaysia), hesitancy (31.5-86.0%; 31.5% in Egypt to 86.0% in Vietnam), convenience (49.7-95.7%; 49.7% in Austria to 95.7% in Malaysia), advice (66.1-97.3%; 66.1% in Austria to 97.3% in Malaysia), and costs (16.0-91.3%; 16.0% in Vietnam to 91.3% in Malaysia). In multivariable regression analysis, several socio-demographic characteristics were identified as associated factors of outcome variables including, i) vaccine effectiveness: younger age, male, urban residence, higher education, and higher income; ii) acceptance: younger age, male, urban residence, higher education, married, and higher income; and iii) hesitancy: male, higher education, employed, unmarried, and lower income. Likewise, the factors associated with vaccination decision-making including i) convenience: younger age, urban residence, higher education, married, and lower income; ii) advice: younger age, urban residence, higher education, unemployed/student, married, and medium income; and iii) costs: younger age, higher education, unemployed/student, and lower income. CONCLUSIONS: Most participants believed that vaccination would effectively control and prevent COVID-19, and they would take vaccinations upon availability. Determinant factors found in this study are critical and should be considered as essential elements in developing COVID-19 vaccination campaigns to boost vaccination uptake in the populations.

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Marzo, R., Ahmad, A., Islam, M., Essar, M., Heidler, P., King, I., Thiyagarajan, A., Jermsittiparsert, K., Songwathana, K., Younus, D., El-Abasiri, R., Biçer, B., Pham, N., Respati, T., Fitriyana, S., Faller, E., Baldonado, A., Billah, M., Aung, Y., Hassan, S., Asad, M., El-Fass, K., Bhattacharya, S., Shrestha, S., Hamza, N., Friedmann, P., Head, M., Lin, Y., Yi, S. (2022). Perceived COVID-19 vaccine effectiveness, acceptance, and drivers of vaccination decision-making among the general adult population: A global survey of 20 countries. https://doi.org/10.1371/journal.pntd.0010103

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Auteur(s)

Roy Rillera Marzo Absar Ahmad Md. Saiful Islam Mohammad Yasir Essar Petra Heidler Isabel King Arulmani Thiyagarajan Kittisak Jermsittiparsert Karnjana Songwathana Delan Ameen Younus Radwa Abdullah El-Abasiri Burcu Küçük Biçer Nhat Tan Pham Titik Respati Susan Fitriyana Erwin M. Faller Aries Moralidad Baldonado Md Arif Billah Yadanar Aung Shehu Muhammad Hassan Muhammad Mujtaba Asad Kareem Ahmed El-Fass Sudip Bhattacharya Sunil Shrestha Nouran Hamza Pascal Friedmann Michael Head Yulan Lin Siyan Yi

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