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Use of hydroxyurea in French-speaking Sub-Saharan Africa

Article scientifique 2025 Anglais

Résumé

The hydroxyurea is a save, affordable and essential medicine for sickle cell disease (SCD), reducing painful crises and mortality. To foster the prescription of hydroxyurea for patients with SCD in sub-Saharan African countries, the scientific advisory board of Drep.Afrique, a non-governmental organization dedicated to SCD in Africa, has developed a therapeutic guideline well suited to conditions on the ground. These guidelines answer three essential questions: which patients should be prioritized for treatment with hydroxyurea, which dose should be used, and what follow-up should be implemented in those low-resources countries? The guidelines are given as in a concise document for easy use by practitioners on the ground, available in English and in French.

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Arlet, J., Bernaudin, F., Dème-Ly, I., Coulibaly, B., Corbasson, A., Diagne, I., Diallo, D., Diop, S., Eposse, C., Galactéros, F., Hermine, O., Kafando, É., Lainé, A., Montalembert, M., Vodouhé, C., Vovor, A., Ranque, B., Tshilolo, L. (2025). Use of hydroxyurea in French-speaking Sub-Saharan Africa. https://doi.org/10.1007/s00277-024-06180-2

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Texte intégral en lecture en ligne, réservé aux abonnés SPHAERO et aux membres de l'institution. Se connecter

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Auteur(s)

Jean-Benoit Arlet Françoise Bernaudin Indou Dème-Ly Binta Coulibaly Anne Corbasson Ibrahima Diagne Dapa A. Diallo Saliou Diop Charlotte Eposse F. Galactéros Olivier Hermine Éléonore Kafando Agnès Lainé Mariane de Montalembert Constant Vodouhé Ahoéfa Vovor Brigitte Ranque Léon Tshilolo

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