Vaccination against COVID-19 and Clinical correlates among a population of psychiatric outpatients

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Introduction Patients suffering from psychiatric disorders represent a population that is particularly at risk of COVID-19-related morbidity and mortality. Vaccination was the most effective strategy to prevent the severe forms of the disease. Objectives We aimed in our study to determine the rate of COVID-19 vaccination and to identify its correlated factors in psychiatric outpatients. Methods This is a descriptive and analytical cross-sectional study conducted on 178 outpatients at the department of psychiatry (Monastir, Tunisia) over a period of one month (from March 2022 to April 2022). Data was collected via a questionnaire focused on two main attributes: (1) sociodemographic and clinical characteristics; (2) questions about the flu vaccination history and its modalities. Results The mean age of our patients was 44.9±13.7 years. The majority of them (81.5%) had a chronic evolution of their psychiatric disorder (> 2 years). Psychosis was the most represented disorder with 57.3% compared to mood disorders and anxiety disorders. Among our population, 73% of the patients received vaccination against COVID-19. The majority got 2 doses (60%), were vaccinated on their own initiative (68%) and by making an appointment (71.4%). Patients with depressive disorders accessed to vaccination program in 100% of cases. The group of psychotic patients had a vaccination rate of 66%. Vaccination was significantly associated with gender (p=0.001), age (p=0.04), marital status (p<10-3), number of children (p=0.002), housing situation (0.018), diagnosis (p<10-3) and treatment (p=0.01) Conclusions Patients with psychiatric disorders experience a distinct burden of the COVID-19 disease. They should therefore be prioritised in vaccine allocation strategies, especially among patients with psychotic disorders. Disclosure of Interest None Declared

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