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Effects of oral hygiene and food intake on tongue swab testing for tuberculosis in South Africa

Article scientifique 2026 Autre

Résumé

Abstract The WHO has recommended tongue swabs (TS) as alternative samples for microbiological diagnosis of tuberculosis. We evaluated the effects of oral hygiene and food/drink intake on TS performance in South Africa. Food/drink intake prior to sampling marginally decreased Mycobacterium tuberculosis DNA signal strength, but neither behaviour decreased diagnostic sensitivity.

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Luabeya, A., Olson, A., As, D., Hadley, K., Wood, R., Mabwe, S., Petersen, C., Yan, A., Weigel, K., Yager, P., Hatherill, M., Cangelosi, G. (2026). Effects of oral hygiene and food intake on tongue swab testing for tuberculosis in South Africa. https://doi.org/10.64898/2026.08.19.26360845

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Auteur(s)

Angelique Kany Kany Luabeya Alaina M. Olson Danelle van As Kate Hadley Rachel C. Wood Simba Mabwe Christel Petersen Alexander J. Yan Kris M. Weigel Paul Yager Mark Hatherill Gerard A. Cangelosi

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