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4th Pediatric Allergy and Asthma Meeting (PAAM)

Article scientifique 2016 Anglais

Résumé

Introduction: Bullous lesions are common skin lesions particularly in childhood. Drug reactions, burns, insect bites, mosquito bites, skin diseases, autoimmune bullous dermatoses and bacterial infections are the most common etiologies. Herein, we report two children who have solitary mastocytoma presented with variable bullous lesions. Case 1: A 3-year old boy admitted to our outpatient department suffering from red, periodically vesicular and bullous lesions on his back of neck since birth. His medical history revealed that he had four attacks characterized by flushing, perioral paleness, and hypotension. The lesion became swollen and itchy when it was rubbed vigorously (positive Darier's sign). Physical examination revealed a bullous lesion (2 3 cm) in his dorsal neck region. Laboratory investigations including CBC, liver and kidney function tests and serum electrolytes were within normal limits. Histopathologic examination of a punch biopsy specimen revealed solitary mastocytoma and the patient is under regular antihistamine treatment. Case 2: A 3-month old boy admitted with complaints of oval, erythematous and periodically changing bullous lesions in his proximal of right ankle since birth. His medical history revealed that the lesion became bullous and itchy when his mother rubbed it vigorously. Physical examination revealed a bullous lesion (1 1 cm) in his left foot. Laboratory investigations for possible etiologic factors were within normal limits. Histopathologic examination of a punch biopsy specimen revealed solitary mastocytoma. The patient is uneventfully under regular follow up. Conclusion: Solitary mastocytomas should be considered in the differential diagnosis of periodically varying bullous reactions in children.

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Yavuz, S., Koc, O., Güngör, A., Gök, F., Hawley, J., O’Brien, C., Thomas, M., Brodlie, M., Michaelis, L., Mota, I., Gáspár, A., Piedade, S., Sampaio, G., Dias, J., Paiva, M., Morais‐Almeida, M., Madureira, C., Lopes, T., Lopes, S., Almeida, F., Sequeira, A., Carvalho, F., Oliveira, J., Gay-Crosier, F., Nenciu, I., Nita, A., Ulmeanu, A., Orăşeanu, D., Zăpucioiu, C., Machinena, A., Sánchez, O., Álvaro‐Lozano, M., Feijoo, R., Blasco, J., Gibert, M., Muñoz, M., Costa, M., Martín, A., Yılmaz, E., Cavkaytar, Ö., Büyüktiryaki, B., Soyer, Ö., Saçkesen, C., Netting, M., El-Merhibi, A., Gold, M., Penttila, I., Giavi, S., Muraro, A., Lauener, R., Mercenier, A., Bersuch, E., Montagner, I., Passioti, M., Celegato, N., Summermatter, S., Nutten, S., Bourdeau, T., Vissers, Y., Papadopoulos, N., Kleij, H., Warmenhoven, H., Ree, R., Pieters, R., Opstelten, D., Schijndel, H., Smit, J., Fitzsimons, R., Timms, V., Toit, G., Kaya, G., Güleç, M., Saldır, M., Şener, O., Hassan, N., Shaaban, H., El-Hariri, H., Mahfouz, A., Gabor, P., Bíró, G., Csaba, K., Chawes, B., Bønnelykke, K., Stokholm, J., Heickendorff, L., Brix, S., Rasmussen, M., Bisgaard, H., Hallas, H., Arianto, L., Pincus, M., Keil, T., Reich, A., Wahn, U., Lau, S., Grabenhenrich, L. (2016). 4th Pediatric Allergy and Asthma Meeting (PAAM). https://doi.org/10.1186/s13601-016-0117-8

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Auteur(s)

Süleyman Tolga Yavuz Ozan Koc Ali Güngör Faysal Gök Jessica E. Hawley Christopher J. O’Brien Matthew F. Thomas Malcolm Brodlie Louise J. Michaelis Inês Mota Angéla Gáspár Susana Piedade Graça Sampaio José Geraldo Dias Miguel Paiva Mário Morais‐Almeida Cristina Madureira Tânia Lopes Susana Lopes Filipa Almeida Alexandra Sequeira Fernanda Carvalho José Inácio de Oliveira Fabienne Gay-Crosier Ioana-Valentina Nenciu Andreia Nita Alexandru Ulmeanu Dumitru Orăşeanu Carmen Zăpucioiu Adrianna Machinena Olga Domínguez Sánchez Montserrat Álvaro‐Lozano Rosa Feijoo Jaime Lozano Blasco Mònica Piquer Gibert M.T. Giner Muñoz M. Dias da Costa Ana Martín Ebru Arık Yılmaz Özlem Cavkaytar Betül Büyüktiryaki Özge Soyer Cansın Saçkesen Merryn Netting Adaweyah El-Merhibi Michael Gold Irmeli Penttila Stavroula Giavi Antonella Muraro Roger Lauener Annick Mercenier Eugen Bersuch Isabella Monia Montagner Maria Passioti Nicolò Celegato Selina Summermatter Sophie Nutten Tristan Bourdeau Yvonne M. Vissers Nikolaos G. Papadopoulos Hanneke van der Kleij Hans Warmenhoven Ronald van Ree Raymond Pieters Dirk Jan E. Opstelten Hans van Schijndel Joost J. Smit Róisín Fitzsimons Victoria Timms George Du Toit Güven Kaya Mustafa Güleç Mehmet Saldır Osman Şener Nagwa Hassan Hala Shaaban Hazem M. El-Hariri Ahmed Kamel Inas E. Mahfouz Papp Gabor G. Bíró K Csaba Bo Chawes Klaus Bønnelykke Jakob Stokholm Lene Heickendorff Susanne Brix Morten Arendt Rasmussen Hans Bisgaard Henrik Wegener Hallas Lambang Arianto Maike Pincus Thomas Keil Andreas Reich Ulrich Wahn Susanne Lau Linus Grabenhenrich

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