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GRANULOMATOSIS WITH POLYANGIITIS WITH BILATERAL FACIAL PALSY AND ORAL ULCERS - AN ATYPICAL PRESENTATION

Article scientifique 2019 Anglais

Résumé

Granulomatosis with Polyangiitis (GPA) is a systemic vasculitis of autoimmune etiology, characterized by the triad: necrotizing granulomatous inflammation of the respiratory tract, disseminated vasculitis and glomerulonephritis. Early diagnosis requires a high level of suspicion, being essential the anatomopathological examination and the presence of antineutrophil cytoplasmic antibodies directed against proteinase 3 (c-ANCA). Among the ANCA - associated vasculitis, peripheral neuropathy is more commonly observed in eosinophilic granulomatosis with polyangiitis (60 – 80%) than in microscopic polyangiitis (40 – 50%) or GPA (20 – 25%). Neuropathy is not usually associated with life threatening manifestations, usually affects motor nerves and is long-lasting.

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Ramos, A., Bezerra, A., Luz, S., Silva, F., HOLANDA, R., Lucena, L., MENEZES, B., BRITO, A., UNIFACISA, C. (2019). GRANULOMATOSIS WITH POLYANGIITIS WITH BILATERAL FACIAL PALSY AND ORAL ULCERS - AN ATYPICAL PRESENTATION. https://doi.org/10.5151/sbr2019-113

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Auteur(s)

Anna Maria Moreira Ramos Aristócles Hítallo Bezerra Sávio Nixon Passos Luz Filipe José da Silva RADMILA AGRA CARIRY TARGINO DE HOLANDA Larissa Neves de Lucena BEATRIZ ALVES DE MENEZES ANA CAROLINA ARRUDA MEIRA BRITO CAMPINA GRANDE IGOR DE MELO CASTRO UNIFACISA

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