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Cardiovascular disease in North African women: insights from the Middle East African Women CardioVascular Disease (MEA-WCVD) registry

Article scientifique 2025 Anglais

Résumé

Cardiovascular disease (CVD) is a major health burden worldwide, yet gender-specific data from the Middle East and North Africa (MENA) region remain scarce. The Middle East African Registry of Women with Cardiovascular Disease enrolled adult patients with coronary heart disease (CHD), heart failure (HF), atrial fibrillation (AF), or valvular heart disease (VHD) across Tunisia between May and July 2023. Of 15,366 patients, 37.6% were women. Compared with men, women were older, had lower socioeconomic status, and presented with more obesity, hypertension, diabetes, dyslipidemia, and sedentary lifestyle but smoked less. CHD was less frequent in women, while AF and VHD were more prevalent. Women underwent fewer coronary angiographies and percutaneous interventions, experienced longer delays, and received fewer guideline-based therapies, including dual antiplatelet agents and high-intensity statins. Among HF patients, women more often had preserved ejection fraction and higher hospitalization rates. These results highlight persistent gender inequities in CVD care in Tunisia.

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Charfeddine, S., Abid, L., Chenik, S., Krayen, I., Haddar, O., Ghrab, A., Boudiche, S., Touati, H., Ayedi, O., Ammar, M., Halima, M., Ayed, H., Brahim, A., ElAyech, F., Allouche, E., Thabet, H., Mahfoudhi, H., Jabloun, T., Ayadi, Y., Ayadi, A., Romdhani, G., Gargouri, H., Zidi, O., Guedri, M., Tlili, R., Trabelsi, B., Hammami, S., Othmen, R., Antit, S., Saidane, S., Dardour, S., Iddir, S., Kharrat, E., Cheikhrouhou, A., Derwich, M., Mrabet, A., Lassoued, T., Rekik, E., Gmiha, S., Laribi, N., Lamine, H., Triki, Z., Ayari, S., Boujelbene, F., Boughzéla, E., Rekik, H., Ameur, I., Abid, S., Oueghlani, K., Haggui, A., Halima, A., Ouechtati, W., Bennour, E., Hammami, R., Jabeur, M., Zaïri, I., Drissa, M., Addad, F., Milouchi, S., Mourali, M., Slima, H., Bezdah, L., Neffati, E., Ameur, Y., Kraiem, S., Kachboura, S., Kammoun, I., Zakhama, L., Amor, H., Hamda, K., Messoudi, Y., Hlima, N., Dahmani, R., Gamra, H., Elhadj, Z., Denguir, H., Ghorbel, C., Mechri, N., Hajri, S., Mebazaa, A., Dhaou, F., Trigui, M., Fehri, W., Abdessalem, S. (2025). Cardiovascular disease in North African women: insights from the Middle East African Women CardioVascular Disease (MEA-WCVD) registry. https://doi.org/10.3389/fcvm.2025.1577793

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Auteur(s)

S. Charfeddine Leïla Abid Sarra Chenik Iheb Ben Krayen Oussama Haddar Aiman Ghrab S. Boudiche Haithem Touati Oumaima Ayedi Mohamed Amine Ammar Manel Ben Halima Houssem Ben Ayed Asma Brahim Faten ElAyech E. Allouche Houssem Thabet Houaida Mahfoudhi Taha Yessine Jabloun Yasmine Ayadi Asma Ayadi Ghassen Romdhani Héla Gargouri Oumayma Zidi Mohamed Ali Guedri Rami Tlili Bechir Trabelsi Selim Hammami Rim Othmen Saoussen Antit Syrine Saidane Sirine Dardour Skander Iddir Elyes Kharrat Anis Cheikhrouhou Marcin Derwich Amal Mrabet Taha Lassoued Emna Rekik Sahar Gmiha Niez Laribi Hakim Lamine Zied Triki Samir Ayari Fatma Boujelbene Essia Boughzéla Hajer Rekik Ines Ben Ameur Syrine Abid Khalil Oueghlani Abdeddayem Haggui Afef Ben Halima Wejdène Ouechtati Emna Bennour Rania Hammami Mariem Jabeur Ihsen Zaïri Mariem Drissa Faouzi Addad Sami Milouchi Mohamed Sami Mourali H. Ben Slima Leila Bezdah Elyes Neffati Youssef Ben Ameur Sondes Kraiem Salem Kachboura Ikram Kammoun Lilia Zakhama Hassen lbn Hadj Amor Khaldoun Ben Hamda Yosra Messoudi Nejah Ben Hlima Rana Dahmani Habib Gamra Zied Ibn Elhadj Hichem Denguir C.H. Ghorbel Nizar Mechri Samia Ernez Hajri Alexandre Mebazaa Fedi Ben Dhaou Maroua Trigui Wafa Fehri Salem Abdessalem

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