The pattern of hepatectomy and posthepatectomy complications in selected hospitals in Addis Ababa, Ethiopia
Résumé
Abstract Background Hepatic resection is a procedure performed for benign and malignant liver lesions, often involving the removal of liver tissue with or without resection of other organs. Different complications, including bleeding, biliary leakage, liver failure, renal failure and postoperative infections, can occur postoperatively. The outcome of hepatic resection is affected by preoperative, intraoperative and postoperative factors. In Ethiopia, although the demand for hepatectomy is very high, the pattern and factors affecting the outcomes are not well known due to the lack of adequate studies. Methods A facility-based retrospective cross-sectional study was conducted at the Tikur Anbessa and Addis Hiwot hospitals in Addis Ababa, Ethiopia. All eligible and complete patient records registered from March 2016 to March 2021 from both hospitals were included and reviewed. The data were entered and cleaned with Epidata version 3.1 and then exported to and analyzed using SPSS version 23. Descriptive data analysis was performed, and the data are presented in tables, charts and graphs. Binary logistic regression analysis was used to identify associated factors, and a p value < 0.05 indicated statistical significance. Results A total of 97 patients underwent hepatic resection. There were 50 females and 47 males. A significantly greater proportion (26.8%) of the patients who underwent hepatectomy in both hospitals developed complications. Primary hemorrhage and postoperative infection were the most common complications and occurred in 17.5% and 11.3%, respectively, of the patients. Other complications that occurred included bile leakage, ascites, and organ failure, and some patients (5.2%) developed multiple complications. Hepatectomy performed for liver metastases with simultaneous resection of the primary tumor was significantly associated with postoperative complications (AOR = 16.01; 95% CI = 1.66-155.94). Conclusions A significantly greater proportion of patients developed complications, of which primary hemorrhage and infection were the most common complications. Postoperative complications were greater in patients who underwent simultaneous resection of the primary tumor and liver metastases.
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