Novel Neurological and Anti-epileptic Drug of Combined Valproic acid and Topiramate (TopVal).

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In this communication we demonstrate the development of a novel neurological compound of combined valproic acid and topiramate (TopVal) which might offer a potential therapeutic option for epilepsy, refractory epilepsy as well as other neurological diseases currently managed by either drug. A lower administered dose might help to achieve a higher safety profile when enrolled for randomized clinical trials against either drug.

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