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THE RISK OF CANCER DEVELOPMENT IN SJOGREN SYNDROME

Article scientifique 2019 Anglais

Résumé

Sjögren Syndrome (SS) is a chronic inflammatory autoimmune condition related to progressive lymphocytic infiltration among exocrine organs, preferably salivary and lachrymal glandules, which has structural and secretory disfunction. The disease has major incidence in women, reaching 9:1 ratio, mainly on 4th - 6th decades. It is classified as primary SS form, characterized by glandular dysfunction; and secondary SS form, associated with other autoimmune diseases. 5-10% patients will develop non-Hodgkin B cells malign lymphoma, representing an increased risk of 44 times in comparison with general population. The relation between SS and other cancer types in poorly described in the literature. The main of this study was to evaluate the prevalence of cancer in SS population.

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Machado, A., Lopes, M., Rosa, E., CORANDIN, R., Ordinola, A., Gasparini, A., Augusto, J., Kamada, D., Gandarillas, G., DUTRA, G., Trevisani, V. (2019). THE RISK OF CANCER DEVELOPMENT IN SJOGREN SYNDROME. https://doi.org/10.5151/sbr2019-607

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Auteur(s)

Adriana Cristiane Machado Maria Lúcia Lemos Lopes Eduardo Souza Rosa RAFAEL CORANDIN Amanda Ayako Minemura Ordinola André Felipe Gasparini Juliana Venturini Augusto Daniela Midori Kamada Gabriela Mendia Gandarillas GABRIELA COELHO DUTRA Virgínia Fernandes Moça Trevisani

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