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A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice

Article scientifique 2018 Anglais

Résumé

Rheumatoid arthritis, an auto-immune disorder, is characterized by chronic inflammation of the joints, synovial hyperplasia and bone erosion. These pathological features are promoted by a synovial microenvironment featuring B-cell and T-cell infiltrate, synovial fibroblasts and an intricate network of pro-inflammatory cellular messengers – prominent molecular role-players that represent critical targets in the pharmacotherapy of the disease. This review offers a brief overview of the etiopathology of rheumatoid arthritis while focussing on the practical aspects of methotrexate and glucocorticoid use that are of relevance for primary practice.

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Brand, L., Wolmarans, D., Brand, S. (2018). A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice. https://doi.org/10.4102/safp.v60i2.4839

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Auteur(s)

Linda Brand De Wet Wolmarans S Brand

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