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Evaluation of crude larval protein and recombinant somatic protein 26/23 (rHcp26/23) immunization against Haemonchus contortus in sheep

Article scientifique 2017 Anglais

Résumé

AIM: for immunization to control sheep hemonchosis. MATERIALS AND METHODS: on day 42. An unvaccinated positive control group was challenged with L3 in the meantime. An unvaccinated negative control group was not challenged. RESULTS: Fecal egg count reduction taking after challenge for rHcp26/23 and larval antigens was 92.2% and 38.2%, respectively, compared with the positive control group. Vaccine incited protection in rHcp26/23 and larval immunization was reflected in significant (p<0.05) decreases in worm burden; 59.9% and 40.1%, respectively. CONCLUSION: Recombinant rHcp26/23 vaccine induced a partial immune response and had immune-protective effect against sheep hemonchosis.

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Kandil, O., Abdelrahman, K., Shalaby, H., Hendawy, S., Ezz, N., Nassar, S., Miller, J. (2017). Evaluation of crude larval protein and recombinant somatic protein 26/23 (rHcp26/23) immunization against Haemonchus contortus in sheep. https://doi.org/10.14202/vetworld.2017.758-763

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Auteur(s)

Omnia M. Kandil Khaled A. Abdelrahman Hatem A. Shalaby Seham H. M. Hendawy Nadia M. T. Abu El Ezz Somia A. Nassar James E. Miller

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