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Cryptococcal meningitis: A neglected NTD?

Article scientifique 2017 Anglais

Résumé

Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation. Of these OIs, cryptococcal meningitis, a deadly invasive fungal infection, continues to affect hundreds of thousands of HIV patients with advanced disease each year and is responsible for an estimated 15%-20% of all AIDS-related deaths Yet cryptococcal meningitis ranks amongst the most poorly funded "neglected" diseases in the world, receiving 0.2% of available relevant research and development (R&D) funding, according to Policy Cures' 2016 Global Funding of Innovation for Neglected Diseases (G-Finder) Report

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Molloy, S., Chiller, T., Greene, G., Burry, J., Govender, N., Kanyama, C., Mfinanga, S., Lesikari, S., Mapoure, Y., Kouanfack, C., Sini, V., Temfack, E., Boulware, D., Dromer, F., Denning, D., Day, J., Stone, N., Bicanic, T., Jarvis, J., Lortholary, O., Harrison, T., Jaffar, S., Loyse, A. (2017). Cryptococcal meningitis: A neglected NTD?. https://doi.org/10.1371/journal.pntd.0005575

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Auteur(s)

Síle F. Molloy Tom Chiller Greg Greene Jessica Burry Nelesh P. Govender Cecilia Kanyama Sayoki Mfinanga Sokoine Lesikari Yacouba Njankouo Mapoure Charles Kouanfack Victor Sini Elvis Temfack David R. Boulware Françoise Dromer David W. Denning Jeremy Day Neil Stone Tihana Bicanic Joseph N Jarvis Olivier Lortholary Thomas S. Harrison Shabbar Jaffar Angela Loyse

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