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Giant primary angiosarcoma of an adolescent girl’s breast diagnosed postmortem: a case report

Article scientifique 2020 Anglais

Résumé

BACKGROUND: Angiosarcoma is an endothelial malignant tumor; angiosarcoma located in the breast is extremely rare, less than 0.01%. We report a case of a giant angiosarcoma diagnosed postmortem in a 16-year-old girl in a resource-constrained country. CASE PRESENTATION: A 16-year-old black African girl was admitted for altered consciousness and a left breast tumor. She was admitted in a state of apparent death. Her death was confirmed on clinical examination. A postmortem biopsy of the mammary tumor showed standard histology of a proliferation of fusiform or rounded tumor cells in places, which were not very cohesive with marked anisokaryosis and numerous foci of tumor necrosis. Immunohistochemistry showed a positivity of CD31 and factor VIII markers with a proliferation index (Ki-67) estimated at 30%. CONCLUSION: Primary angiosarcoma of the breast is exceptional in adolescents and has a poor prognosis, especially in countries with limited resources.

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Darré, T., Brun, L., Séidou, F., Djiwa, T., Ballé, M., Napo‐Koura, G. (2020). Giant primary angiosarcoma of an adolescent girl’s breast diagnosed postmortem: a case report. https://doi.org/10.1186/s13256-020-02403-y

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Auteur(s)

Tchin Darré Luc Brun Falilath Séidou Toukilnan Djiwa Marie Claire Ballé Gado Napo‐Koura

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