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Adipocytokines in obese Ghanaian subjects with or without type 2 diabetes

Article scientifique 2018 Anglais

Résumé

OBJECTIVE: This study aimed to evaluate serum leptin and high sensitivity C-reactive protein (hsCRP) concentrations in obese Ghanaians with or without type 2 diabetes and to find out the extent to which their levels are influenced by underlying disorders. RESULTS: Obese subjects with type 2 diabetes had lower leptin but higher hsCRP levels compared with obese non-diabetic controls. There were negative correlations within the control group for glucose vs % muscle mass (r = - 0.378, p = 0.016), leptin vs % muscle mass (r = - 0.555, p = 0.001) and within the obese diabetic group for leptin vs % muscle mass (r = - 0.602, p = 0.001). Obese persons without diabetes were about three times more likely to have higher leptin levels compared with their obese diabetic counterparts (Odds ratio = 3.315, p < 0.001). Obese females independently had a tenfold increase in leptin levels compared with obese males.

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Adams, Y., Ofori, E., Asare‐Anane, H., Amanquah, S., Ababio, G., Abendau, E., Nabia, R. (2018). Adipocytokines in obese Ghanaian subjects with or without type 2 diabetes. https://doi.org/10.1186/s13104-018-3149-4

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Auteur(s)

Yussif Adams Emmanuel Kwaku Ofori Henry Asare‐Anane Seth D. Amanquah Grace K. Ababio Emmanuel Abendau Richard Nabia

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